Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophages
about
In vitro and in vivo characterization of anthrax anti-protective antigen and anti-lethal factor monoclonal antibodies after passive transfer in a mouse lethal toxin challenge model to define correlates of immunityCharacterization of a therapeutic model of inhalational anthrax using an increase in body temperature in New Zealand white rabbits as a trigger for treatmentAnthrax vaccination strategiesSelection of a macaque Fab with framework regions like those in humans, high affinity, and ability to neutralize the protective antigen (PA) of Bacillus anthracis by binding to the segment of PA between residues 686 and 694.Correlation between lethal toxin-neutralizing antibody titers and protection from intranasal challenge with Bacillus anthracis Ames strain spores in mice after transcutaneous immunization with recombinant anthrax protective antigen.Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin.Immunogenicity of Bacillus anthracis protective antigen domains and efficacy of elicited antibody responses depend on host genetic background.Neutralizing monoclonal antibodies directed against defined linear epitopes on domain 4 of anthrax protective antigenNon-human primate immune libraries combined with germline humanization: an (almost) new, and powerful approach for the isolation of therapeutic antibodies.Comparison of three anthrax toxin neutralization assaysSelect human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge.Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFNγ.New developments in vaccines, inhibitors of anthrax toxins, and antibiotic therapeutics for Bacillus anthracis.Protective antigen-specific memory B cells persist years after anthrax vaccination and correlate with humoral immunityA requirement for FcγR in antibody-mediated bacterial toxin neutralization.Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthraxA monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1Prophylaxis and therapy of inhalational anthrax by a novel monoclonal antibody to protective antigen that mimics vaccine-induced immunity.Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity.Antibodies against anthrax: mechanisms of action and clinical applications.Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum.Analysis of defined combinations of monoclonal antibodies in anthrax toxin neutralization assays and their synergistic action.Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerizationMonoclonal antibodies and toxins--a perspective on function and isotype.The potential of antibody-mediated immunity in the defence against biological weapons.MHC class II and non-MHC class II genes differentially influence humoral immunity to Bacillus anthracis lethal factor and protective antigen.Disease-enhancing antibodies improve the efficacy of bacterial toxin-neutralizing antibodiesUnique Inflammatory Mediators and Specific IgE Levels Distinguish Local from Systemic Reactions after Anthrax Vaccine Adsorbed VaccinationAntibody-enhanced, Fc gamma receptor-mediated endocytosis of Clostridium difficile toxin AAnti-toxin antibodies in prophylaxis and treatment of inhalation anthrax.Analysis of the Fc gamma receptor-dependent component of neutralization measured by anthrax toxin neutralization assays.Neutralizing antibodies and persistence of immunity following anthrax vaccination.The promise and challenge of epitope-focused vaccines.Evidence for Complex Formation of the Bacillus cereus Haemolysin BL Components in Solution.Effect of Analgesics on Monoclonal Antibody Ascites Production in Mice Administered Upon Recognition of Pain
P2860
Q28383065-FA546AE8-73E4-45A8-AA5A-66477F09722FQ28387882-2865E58D-D581-4485-953C-185944DFB6BFQ28392248-4E5B7C63-1115-42E5-8C14-363A0F73605BQ33220467-ECED0197-6635-44F4-8E23-1001D852EC6CQ33230047-84B0C65D-40C3-4D99-A681-76B3FBD4E743Q33306246-35BFCAE1-55FA-4BC3-9E12-31B9AD21F1A5Q33334776-ECC2D63B-9527-4751-A078-9D803F0351B0Q33496407-96A3FE47-B02C-4785-8691-DF2FCA1BC7D7Q33523442-258D3C2A-3CCE-431E-BE71-3DFF1D2F0E42Q33550670-147A51CD-83ED-46F6-B343-0F7DF11C0773Q33936452-D11D4BBC-BD90-4079-9E9B-F952B80447F8Q34000070-861129B0-D9CB-47B1-95F9-7C11C6812CA5Q34066161-1BD1D48B-425B-4950-AD26-0C80560F9013Q34101803-11A6BE4E-750F-46E6-B907-A3C8CF3E88D9Q34243378-CDFBDFF5-94F8-41DF-9E8A-48B921D0E068Q34334451-D078C4AD-FB2C-4AB1-9654-5E2C15305484Q34721109-42DB3893-C966-4C56-84C0-C5203D3D5A4BQ35073821-441404B8-BCE4-42F0-A78B-407BAB7A868CQ35599606-EEE5D5BD-D730-4BD3-AEEC-D4AF5C26C413Q35610439-4E0D7D1C-1EC4-493F-9CFC-96F74274C5F7Q35869311-3F64344A-F70E-4CEA-9141-BD8DB8DFEEB7Q35940722-3C317CF8-B6A2-4A58-B38A-50EC70280E2EQ36007463-768185F3-59C2-4353-8916-7AE2FFFF06E6Q36099489-828549E4-0AC0-4227-B43E-3A4A0C0985CBQ36273411-8F323602-0A93-48EF-A7B7-97F3FCC24E5FQ36482706-06BB470F-E107-40C6-A99C-8D060459F884Q36786293-B26FCF91-3D52-49A1-AF81-26D4CC924157Q37163693-3D534E94-DF17-4DED-A44B-C7E1A286BB3FQ37204536-2535DE3F-6C51-4B77-BBEF-A238ECE94E74Q37262118-D4013010-F480-4C8D-A738-2C5E8AA37348Q37374655-D8D8B67F-4728-4B42-B192-DDAF089F5F2EQ40318810-FAB6B1D5-1A5F-4690-BD28-9516875F43B7Q40722956-AA18780D-6DBC-46A3-B075-D1CEC4E49EFDQ41669190-6EA7F034-F3D1-467C-BF63-E3612D5C892BQ59047330-6FBE001B-D396-49F7-8C49-8AE849A0B7EB
P2860
Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophages
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Enhancement of anthrax lethal ...... killing of murine macrophages
@ast
Enhancement of anthrax lethal ...... killing of murine macrophages
@en
type
label
Enhancement of anthrax lethal ...... killing of murine macrophages
@ast
Enhancement of anthrax lethal ...... killing of murine macrophages
@en
prefLabel
Enhancement of anthrax lethal ...... killing of murine macrophages
@ast
Enhancement of anthrax lethal ...... killing of murine macrophages
@en
P2093
P2860
P1476
Enhancement of anthrax lethal ...... killing of murine macrophages
@en
P2093
Arthur M Friedlander
Claudia S Ferreira
George L Spitalny
Leslie S Casey
Nehal Mohamed
Stephen F Little
P2860
P304
P356
10.1128/IAI.72.6.3276-3283.2004
P407
P577
2004-06-01T00:00:00Z