Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.
about
Regulation of cell migration and survival by focal adhesion targeting of Lasp-1Remembrance of dead cells past: discovering that the extracellular matrix is a cell survival factor.c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin.The Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancerCellular responses to Cisplatin-induced DNA damage.Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivoMatrix metalloproteinase-induced genomic instabilityc-Abl is an upstream regulator of acid sphingomyelinase in apoptosis induced by inhibition of integrins αvβ3 and αvβ5.The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabineVinculin activators target integrins from within the cell to increase melanoma sensitivity to chemotherapy.The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cellsThe p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancerscAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of EpacNucleo-cytoplasmic communication in apoptotic response to genotoxic and inflammatory stress.DNA Repair--A Double-Edged Sword in the Genomic Stability of Cancer Cells--The Case of Chronic Myeloid Leukemia.A DNA damage signal activates and derepresses exon inclusion in Drosophila TAF1 alternative splicingDNA damage-induced cell death: lessons from the central nervous system.c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expressionCoordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells.Modulation of Tumor Cell Survival, Proliferation, and Differentiation by the Peptide Derived from Tenascin-C: Implication of β1-Integrin Activation.Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73.Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma.Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.c-Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin-based therapy.Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradationSp1-like sequences mediate human caspase-3 promoter activation by p73 and cisplatin.Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII.MMPs in unusual places.Ex vivo evaluation of imatinib mesylate for induction of cell death on canine neoplastic mast cells with mutations in c-Kit exon 11 via apoptosis.p53 disruption profoundly alters the response of human glioblastoma cells to DNA topoisomerase I inhibition.Delayed activation of Bax by DNA damage in embryonic stem cells with knock-in mutations of the Abl nuclear localization signals.Thymidine-phosphorothioate oligonucleotides induce activation and apoptosis of CLL cells independently of CpG motifs or BCL-2 gene interference.
P2860
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P2860
Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@ast
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@en
type
label
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@ast
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@en
prefLabel
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@ast
Modulation of DNA damage-induc ...... tly mediated by p53 and c-Abl.
@en
P2093
P2860
P356
P1476
Modulation of DNA damage-induc ...... ntly mediated by p53 and c-Abl
@en
P2093
Guizhen Sun
Jean Y J Wang
Michael Doorly
Tony Truong
P2860
P304
10281-10286
P356
10.1073/PNAS.1635435100
P407
P577
2003-08-19T00:00:00Z