Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation

Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation

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http://www.wikidata.org/entity/Q30453740

Q30453740

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The regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes.mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits Identification of RPS14 as a 5q- syndrome gene by RNA interference screen Signaling by target of rapamycin proteins in cell growth control Regulation of mTOR and cell growth in response to energy stress by REDD1.Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.Amino acids as regulators of gene expression mTOR signaling in growth control and disease Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function Glutamatergic Transmission: A Matter of Three The expanding role of mTOR in cancer cell growth and proliferation RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo.La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Nerve growth factor specifically stimulates translation of eukaryotic elongation factor 1A-1 (eEF1A-1) mRNA by recruitment to polyribosomes in PC12 cells Alterations in mammalian target of rapamycin signaling pathways after traumatic brain injury The hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvation Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.TOR signaling.Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells.S6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells.Parallel measurement of dynamic changes in translation rates in single cells.The complex regulation of HIC (Human I-mfa domain containing protein) expression.Role of adenosine 5'-monophosphate-activated protein kinase subunits in skeletal muscle mammalian target of rapamycin signaling.Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.5'UTR variants of ribosomal protein S19 transcript determine translational efficiency: implications for Diamond-Blackfan anemia and tissue variability.Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.Ribosomal protein S19 binds to its own mRNA with reduced affinity in Diamond-Blackfan anemia hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation.mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells.Translational deregulation in PDK-1-/- embryonic stem cells Eukaryotic initiation factor 4F: a vulnerability of tumor cells.Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation mTOR signaling for biological control and cancer.Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation.Telomerase expression abrogates rapamycin-induced irreversible growth arrest of uterine fibroid smooth muscle cells.

P2860

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P2860

Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin, and is independent of S6K1 and rpS6 phosphorylation

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http://www.wikidata.org/entity/Q30453740

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2001 nî lūn-bûn

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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

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2001年論文

@zh-mo

2001年論文

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2001年论文

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