Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.
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Prospects for Improving Brain Function in Individuals with Down SyndromeTiming of therapies for Down syndrome: the sooner, the betterDown Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 HomologuesMonoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndromeSheltering behavior and locomotor activity in 11 genetically diverse common inbred mouse strains using home-cage monitoringPharmacological approaches to improving cognitive function in Down syndrome: current status and considerations.Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome.β1-adrenergic receptor activation enhances memory in Alzheimer's disease modelSex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice.Age-related neurodegeneration and memory loss in down syndrome.From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome.Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists.Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.The need for speed in rodent locomotion analyses.An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.Short-term treatment with the GABAA receptor antagonist pentylenetetrazole produces a sustained pro-cognitive benefit in a mouse model of Down's syndrome.Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome.Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression.Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer's-like memory deficits in the Ts65Dn mouse model of Down syndrome.Neuromodulatory signaling in hippocampus-dependent memory retrieval.Xamoterol impairs hippocampus-dependent emotional memory retrieval via Gi/o-coupled β2-adrenergic signaling.Update of neurotrophic factors in neurobiology of addiction and future directions.Improving Memory and Cognition in Individuals with Down Syndrome.Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist.Dentate gyrus mediates cognitive function in the Ts65Dn/DnJ mouse model of Down syndrome.GABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role of App.Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders.Aging rather than aneuploidy affects monoamine neurotransmitters in brain regions of Down syndrome mouse modelsAttentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome.Rodent models in Down syndrome research: impact and future opportunities.Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.Touchscreen learning deficits in Ube3a, Ts65Dn and Mecp2 mouse models of neurodevelopmental disorders with intellectual disabilities.Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.Adaptation of the Arizona Cognitive Task Battery for use with the Ts65Dn mouse model (Mus musculus) of Down syndrome.Does ceruloplasmin differential express in the brain of Ts65Dn: a mouse mode of Down syndrome?
P2860
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P2860
Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@ast
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@en
type
label
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@ast
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@en
prefLabel
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@ast
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@en
P2093
P2860
P1476
Comprehensive behavioral pheno ...... potential cognitive enhancer.
@en
P2093
Alexander Kleschevnikov
Angelo Encarnacion
Christine Tun
Matthew Priestley
Mehrdad Faizi
Mehrdad Shamloo
Patrick L Bader
Pavel Belichenko
Richard W Tsien
P2860
P304
P356
10.1016/J.NBD.2011.04.011
P577
2011-04-17T00:00:00Z