Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea - Wikidata - awgldk - TriplyDB

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

http://www.wikidata.org/entity/Q30460671

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Sensory hair cell development and regeneration: similarities and differences Cell cycle reactivation of cochlear progenitor cells in neonatal FUCCI mice by a GSK3 small molecule inhibitor.LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.Wnt activation protects against neomycin-induced hair cell damage in the mouse cochlea Lead roles for supporting actors: critical functions of inner ear supporting cells Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles.A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea.Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation Effect of JNK inhibitor SP600125 on hair cell regeneration in zebrafish (Danio rerio) larvae.Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea.Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.Inhibition of H3K9me2 Reduces Hair Cell Regeneration after Hair Cell Loss in the Zebrafish Lateral Line by Down-Regulating the Wnt and Fgf Signaling Pathways.Quantitative High-Resolution Cellular Map of the Organ of Corti.Induction of Functional Hair-Cell-Like Cells from Mouse Cochlear Multipotent Cells.Manipulating cell fate in the cochlea: a feasible therapy for hearing loss.In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1 The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle Sensory hair cell regeneration in the zebrafish lateral line.Histone deacetylase inhibitor induces the expression of select epithelial genes in mouse utricle sensory epithelia-derived progenitor cells.Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies.Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse.Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling Hair cell damage recruited Lgr5-expressing cells are hair cell progenitors in neonatal mouse utricle.Making sense of Wnt signaling-linking hair cell regeneration to development.A simple method for purification of vestibular hair cells and non-sensory cells, and application for proteomic analysis.LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts Gene-expression analysis of hair cell regeneration in the zebrafish lateral line.Sound strategies for hearing restoration.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors.Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult.

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Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

http://www.wikidata.org/entity/Q30460671

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2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

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Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

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type

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Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

@ast

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

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prefLabel

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

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Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

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PNAS.1202774109

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

@en

P2093

Alan G Cheng

http://www.w3.org/2001/XMLSchema#string

Anping Xia

http://www.w3.org/2001/XMLSchema#string

Bryan Kuo

http://www.w3.org/2001/XMLSchema#string

Eric J Liaw

http://www.w3.org/2001/XMLSchema#string

Jian Zuo

http://www.w3.org/2001/XMLSchema#string

John S Oghalai

http://www.w3.org/2001/XMLSchema#string

Makoto M Taketo

http://www.w3.org/2001/XMLSchema#string

Renjie Chai

http://www.w3.org/2001/XMLSchema#string

Roeland Nusse

http://www.w3.org/2001/XMLSchema#string

Taha A Jan

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.

Generalized lacZ expression with the ROSA26 Cre reporter strain

The Wnt signaling pathway in development and disease

Identification of stem cells in small intestine and colon by marker gene Lgr5

p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression

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8167-8172

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10.1073/PNAS.1202774109

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21

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109

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2012-05-04T00:00:00Z

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224915303

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22562792

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3361451

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