Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin.
about
Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two stepsRTX proteins: a highly diverse family secreted by a common mechanismThe adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis.Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain.Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cellsMembrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family.Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells.Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayerBordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme.Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptorThe conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes.Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.Bordetella pertussis adenylate cyclase toxin disrupts functional integrity of bronchial epithelial layers.Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Adenylyl Cyclase Enzyme Domain.
P2860
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P2860
Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin.
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@ast
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@en
type
label
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@ast
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@en
prefLabel
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@ast
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@en
P2093
P2860
P356
P1476
Membrane depolarization preven ...... ussis adenylate cyclase toxin.
@en
P2093
P2860
P304
P356
10.1074/JBC.270.17.9695
P407
P577
1995-04-01T00:00:00Z