Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles - Wikidata - awgldk - TriplyDB

Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles

Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles

http://www.wikidata.org/entity/Q30468270

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Stem Cell Therapy for Sensorineural Hearing Loss, Still Alive?Gene therapy for the inner ear The genetics of hair cell development and regeneration Regenerative medicine for the special senses: restoring the inputs.Sensory hair cell development and regeneration: similarities and differences Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.Lead roles for supporting actors: critical functions of inner ear supporting cells Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles.A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.Supernumerary human hair cells-signs of regeneration or impaired development? A field emission scanning electron microscopy study Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice A central to peripheral progression of cell cycle exit and hair cell differentiation in the developing mouse cristae.Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo.Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing.Hair cell stereociliary bundle regeneration by espin gene transduction after aminoglycoside damage and hair cell induction by Notch inhibition Induction of Functional Hair-Cell-Like Cells from Mouse Cochlear Multipotent Cells.OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development.Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle Sensory hair cell regeneration in the zebrafish lateral line.Cisplatin exposure damages resident stem cells of the mammalian inner ear.Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing.Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse.Macrophage recruitment and epithelial repair following hair cell injury in the mouse utricle.Sensory hair cell death and regeneration in fishes Hair cell damage recruited Lgr5-expressing cells are hair cell progenitors in neonatal mouse utricle.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea Making sense of Wnt signaling-linking hair cell regeneration to development.Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens.LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea In vivo proliferative regeneration of balance hair cells in newborn mice.Stem cell therapy for the inner ear: recent advances and future directions.Gene-expression analysis of hair cell regeneration in the zebrafish lateral line.Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA Sensational placodes: neurogenesis in the otic and olfactory systems.Inner ear supporting cells: rethinking the silent majority.

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P2860

Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles

http://www.wikidata.org/entity/Q30468270

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2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2011年の論文

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Inhibition of Notch activity p ...... ls in the adult mouse utricles

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Inhibition of Notch activity p ...... ls in the adult mouse utricles

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Inhibition of Notch activity p ...... ls in the adult mouse utricles

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JNEUROSCI.2057-11.2011

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Journal of Neuroscience

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Inhibition of Notch activity p ...... ls in the adult mouse utricles

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P2093

Clifford R Hume

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Elizabeth C Oesterle

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Jennifer S Stone

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Justin S Golub

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Tot Bui Nguyen

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Vincent Lin

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P2860

Notch signalling pathway mediates hair cell development in mammalian cochlea

Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.

The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

A new mathematical model for relative quantification in real-time RT-PCR

Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination

Math1: an essential gene for the generation of inner ear hair cells

Math1 regulates development of the sensory epithelium in the mammalian cochlea

The canonical Notch signaling pathway: unfolding the activation mechanism.

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10.1523/JNEUROSCI.2057-11.2011

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43

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3235543

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