The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells. - Wikidata - awgldk - TriplyDB

The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.

The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.

http://www.wikidata.org/entity/Q30476179

about

Association of Grb7 with phosphoinositides and its role in the regulation of cell migration Collective cell migration drives morphogenesis of the kidney nephron Fluid-flow-induced mesenchymal stem cell migration: role of focal adhesion kinase and RhoA kinase sensors FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies Mechanism of Focal Adhesion Kinase Mechanosensing Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen Polarized actin structural dynamics in response to cyclic uniaxial stretch.Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells.Distinct signaling mechanisms regulate migration in unconfined versus confined spaces Cell Structure Controls Endothelial Cell Migration under Fluid Shear Stress A Semi-Automatic Method for Image Analysis of Edge Dynamics in Living Cells Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.Molecular control of cytoskeletal mechanics by hemodynamic forces.Mapping the dynamics of shear stress-induced structural changes in endothelial cells.Micropatterned structural control suppresses mechanotaxis of endothelial cells Arterial shear stress regulates endothelial cell-directed migration, polarity, and morphology in confluent monolayers.Weak force stalls protrusion at the leading edge of the lamellipodium.Substrate rigidity regulates the formation and maintenance of tissues.Golgi polarization in a strong electric field Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates Dynamic motion of paxillin on actin filaments in living endothelial cells alpha4 beta1-Integrin regulates directionally persistent cell migration in response to shear flow stimulation.Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions.Piezo1 integration of vascular architecture with physiological force.A Validated Multiscale In-Silico Model for Mechano-sensitive Tumour Angiogenesis and Growth.Requirement of Ca2+ influx- and phosphatidylinositol 3-kinase-mediated m-calpain activity for shear stress-induced endothelial cell polarity.BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21 CIP1 and p27 KIP1 regulation.Manipulating the microvasculature and its microenvironment.Lymphatic endothelial cells adapt their barrier function in response to changes in shear stress.Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression Shear-induced force transmission in a multicomponent, multicell model of the endothelium Nanotopographical control of stem cell differentiation.Shear force at the cell-matrix interface: enhanced analysis for microfabricated post array detectors.Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis.Forcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing.Interstitial flow influences direction of tumor cell migration through competing mechanisms.Wall shear stress effects on endothelial-endothelial and endothelial-smooth muscle cell interactions in tissue engineered models of the vascular wall.

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P2860

The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.

http://www.wikidata.org/entity/Q30476179

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2002 nî lūn-bûn

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Proceedings of the National Academy of Sciences of the United States of America

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The role of the dynamics of fo ...... anotaxis of endothelial cells.

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P2093

Dong Cho Han

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Jun-Lin Guan

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Peter Butler

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Shu Chien

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Shunichi Usami

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Song Li

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Yingli Hu

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Yingxiao Wang

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P2860

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Cell migration: a physically integrated molecular process

Integrins: versatility, modulation, and signaling in cell adhesion

Signaling through focal adhesion kinase

Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

Integrins: emerging paradigms of signal transduction

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

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10.1073/PNAS.052018099

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