Sox2 induces neuronal formation in the developing mammalian cochlea.
about
Early development of the vertebrate inner earThe genetics of hair cell development and regenerationMolecular mechanisms of inner ear developmentSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Making connections in the inner ear: recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cellsHuman adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applicationsWhere hearing starts: the development of the mammalian cochleaGATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochleaEYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner earInner ear development: building a spiral ganglion and an organ of Corti out of unspecified ectodermThe molecular basis of making spiral ganglion neurons and connecting them to hair cells of the organ of CortiEvolving gene regulatory networks into cellular networks guiding adaptive behavior: an outline how single cells could have evolved into a centralized neurosensory system.Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly.Round window membrane intracochlear drug delivery enhanced by induced advection.Stem cell therapy for the inner ear: recent advances and future directions.Gene-expression analysis of hair cell regeneration in the zebrafish lateral line.Expression and function of scleraxis in the developing auditory systemEarly otic development depends on autophagy for apoptotic cell clearance and neural differentiation.TAK1 expression in the cochlea: a specific marker for adult supporting cells.Sox2 up-regulation and glial cell proliferation following degeneration of spiral ganglion neurons in the adult mouse inner ear.AKT signaling mediates IGF-I survival actions on otic neural progenitors.RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development.Directing human induced pluripotent stem cells into a neurosensory lineage for auditory neuron replacement.Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea.SOX2 is required for inner ear neurogenesis.Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear.The prosensory function of Sox2 in the chicken inner ear relies on the direct regulation of Atoh1.Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neuronsHMGA2, the architectural transcription factor high mobility group, is expressed in the developing and mature mouse cochlea.Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells.Culture of embryonic mouse cochlear explants and gene transfer by electroporation.SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis.Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathwayDynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea.Sox2 in the differentiation of cochlear progenitor cells.Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation.SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors.Ectopic expression of activated notch or SOX2 reveals similar and unique roles in the development of the sensory cell progenitors in the mammalian inner ear.Progression of neurogenesis in the inner ear requires inhibition of Sox2 transcription by neurogenin1 and neurod1.Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance
P2860
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P2860
Sox2 induces neuronal formation in the developing mammalian cochlea.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Sox2 induces neuronal formation in the developing mammalian cochlea.
@ast
Sox2 induces neuronal formation in the developing mammalian cochlea.
@en
type
label
Sox2 induces neuronal formation in the developing mammalian cochlea.
@ast
Sox2 induces neuronal formation in the developing mammalian cochlea.
@en
prefLabel
Sox2 induces neuronal formation in the developing mammalian cochlea.
@ast
Sox2 induces neuronal formation in the developing mammalian cochlea.
@en
P2093
P2860
P1476
Sox2 induces neuronal formation in the developing mammalian cochlea.
@en
P2093
Chandrakala Puligilla
Matthew W Kelley
Stephan D Brenowitz
P2860
P304
P356
10.1523/JNEUROSCI.3852-09.2010
P407
P577
2010-01-01T00:00:00Z