Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes.
about
Visualization and targeted disruption of protein interactions in living cellsCationic membrane peptides: atomic-level insight of structure-activity relationships from solid-state NMRIon Channels Made from a Single Membrane-Spanning DNA Duplex.Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules.Arginine residues at internal positions in a protein are always chargedMatrix stiffness affects endocytic uptake of MK2-inhibitor peptidesStructure and mechanism of beta-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy.Maximally asymmetric transbilayer distribution of anionic lipids alters the structure and interaction with lipids of an amyloidogenic protein dimer bound to the membrane surfaceUnassisted transport of N-acetyl-L-tryptophanamide through membrane: experiment and simulation of kinetics.Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis.Water-protein interactions of an arginine-rich membrane peptide in lipid bilayers investigated by solid-state nuclear magnetic resonance spectroscopy.Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells.Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR.Water-mediated ion-ion interactions are enhanced at the water vapor-liquid interface.The N-terminus of the prion protein is a toxic effector regulated by the C-terminus.An unusual cell penetrating peptide identified using a plasmid display-based functional selection platform.Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.Structure and dynamics of cationic membrane peptides and proteins: insights from solid-state NMR.Implicit membrane treatment of buried charged groups: application to peptide translocation across lipid bilayers.Conjugation to the cell-penetrating peptide TAT potentiates the photodynamic effect of carboxytetramethylrhodamine.Electrostatics of deformable lipid membranes.Modeling kinetics and equilibrium of membranes with fields: milestoning analysis and implication to permeation.Reversible sheet-turn conformational change of a cell-penetrating peptide in lipid bilayers studied by solid-state NMRTat-Mediated Peptide Intervention in Analgesia and Anesthesia.Cell-penetrating peptide induces leaky fusion of liposomes containing late endosome-specific anionic lipid.Effect of particle diameter and surface composition on the spontaneous fusion of monolayer-protected gold nanoparticles with lipid bilayers.Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice.Microsecond molecular dynamics simulations of lipid mixing.Reconciling structural and thermodynamic predictions using all-atom and coarse-grain force fields: the case of charged oligo-arginine translocation into DMPC bilayersA C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes.Translocation thermodynamics of linear and cyclic nonaarginine into model DPPC bilayer via coarse-grained molecular dynamics simulation: implications of pore formation and nonadditivity.Modeling of the endosomolytic activity of HA2-TAT peptides with red blood cells and ghosts.Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions.Overcoming the challenges in the effective delivery of chemotherapies to CNS solid tumors.Electrochemical impedimetric biosensor based on a nanostructured polycarbonate substrate.Molecular mechanisms in the dramatic enhancement of HIV-1 Tat transduction by cationic liposomes.Penetration of HIV-1 Tat47-57 into PC/PE Bilayers Assessed by MD Simulation and X-ray Scattering.HIV-1 Tat membrane interactions probed using X-ray and neutron scattering, CD spectroscopy and MD simulationsInsights into buforin II membrane translocation from molecular dynamics simulations.Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease
P2860
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P2860
Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes.
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Molecular dynamics simulations ...... eptide across lipid membranes.
@ast
Molecular dynamics simulations ...... eptide across lipid membranes.
@en
type
label
Molecular dynamics simulations ...... eptide across lipid membranes.
@ast
Molecular dynamics simulations ...... eptide across lipid membranes.
@en
prefLabel
Molecular dynamics simulations ...... eptide across lipid membranes.
@ast
Molecular dynamics simulations ...... eptide across lipid membranes.
@en
P2860
P356
P1476
Molecular dynamics simulations ...... eptide across lipid membranes.
@en
P2093
Angel E Garcia
Henry D Herce
P2860
P304
20805-20810
P356
10.1073/PNAS.0706574105
P407
P577
2007-12-18T00:00:00Z