Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. - Wikidata - awgldk - TriplyDB

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

http://www.wikidata.org/entity/Q30483969

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Protective effects and mechanisms of sirtuins in the nervous system The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity Redox regulation of SIRT1 in inflammation and cellular senescence The promise and perils of HDAC inhibitors in neurodegeneration Acetylation of NDPK-D Regulates Its Subcellular Localization and Cell Survival Sirt1 promotes axonogenesis by deacetylation of Akt and inactivation of GSK3 Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets A potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neurons SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation Mammalian sirtuins: biological insights and disease relevance Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration.SIRT1 is essential for normal cognitive function and synaptic plasticity Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.Acetylation of tau inhibits its degradation and contributes to tauopathy SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells.Sirtuins: guardians of mammalian healthspan.Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling.miR-34a regulates mouse neural stem cell differentiation Epigenetic regulation of the neural transcriptome and alcohol interference during development.Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging SIRT1 regulates dendritic development in hippocampal neurons.Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer Programmed hyperphagia secondary to increased hypothalamic SIRT1 Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.SIRT1 regulation of wakefulness and senescence-like phenotype in wake neurons Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner.Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cells Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress.The expression and correlation of SIRT1 and Phospho-SIRT1 in colorectal cancer.Metabolic circuits in neural stem cells.Combined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development.SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner.Emerging beneficial roles of sirtuins in heart failure.SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression.Expression of SIRT1 and DBC1 in Developing and Adult Retinas

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Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

http://www.wikidata.org/entity/Q30483969

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@ast

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@en

type

label

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@ast

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@en

prefLabel

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@ast

Histone deacetylase SIRT1 modu ...... by its nuclear translocation.

@en

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PNAS.0800612105

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Proceedings of the National Academy of Sciences of the United States of America

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Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation

@en

P2093

Hiroyuki Matsumoto

http://www.w3.org/2001/XMLSchema#string

Makoto Sato

http://www.w3.org/2001/XMLSchema#string

Masaya Tanno

http://www.w3.org/2001/XMLSchema#string

Shin Hisahara

http://www.w3.org/2001/XMLSchema#string

Shun Shimohama

http://www.w3.org/2001/XMLSchema#string

Susumu Chiba

http://www.w3.org/2001/XMLSchema#string

P2860

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

The Hes gene family: repressors and oscillators that orchestrate embryogenesis

Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

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15599-15604

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scholarly article

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10.1073/PNAS.0800612105

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P433

40

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105

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Yoshiyuki Horio

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2008-09-30T00:00:00Z

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23294099

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18829436

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P921

Nuclear receptor corepressor 1

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2563076

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