The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.
about
Highly efficient protein misfolding cyclic amplificationTwo amyloid States of the prion protein display significantly different folding patternsConformational switching within individual amyloid fibrils.Distinct type of transmission barrier revealed by study of multiple prion determinants of Rnq1.Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.Dissociation of infectivity from seeding ability in prions with alternate docking mechanism.The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance.Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c).Contrasting Effects of Two Lipid Cofactors of Prion Replication on the Conformation of the Prion ProteinHighly neurotoxic monomeric α-helical prion protein.PrP charge structure encodes interdomain interactionsPurification and fibrillation of full-length recombinant PrP.Prion nucleation site unmasked by transient interaction with phospholipid cofactor.Role of metal ions in aggregation of intrinsically disordered proteins in neurodegenerative diseases.Prion processing: a double-edged sword?Evaluation of infective property of recombinant prion protein amyloids in cultured cells overexpressing cellular prion protein.Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria.Purification and Fibrillation of Full-Length Recombinant PrP.
P2860
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P2860
The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@ast
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@en
type
label
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@ast
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@en
prefLabel
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@ast
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@en
P2093
P2860
P1476
The polybasic N-terminal regio ...... ar and fibrillar forms of PrP.
@en
P2093
Ilia V Baskakov
Natallia Makarava
Regina Savtchenko
Valeriy G Ostapchenko
P2860
P304
P356
10.1016/J.JMB.2008.08.073
P407
P577
2008-09-04T00:00:00Z