Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins.
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Functional role of transient conformations: Rediscovering "chronosteric effects" thirty years laterThe Plastic Energy Landscape of Protein Folding: A TRIANGULAR FOLDING MECHANISM WITH AN EQUILIBRIUM INTERMEDIATE FOR A SMALL PROTEIN DOMAINCrystallographic and Nuclear Magnetic Resonance Evaluation of the Impact of Peptide Binding to the Second PDZ Domain of Protein Tyrosine Phosphatase 1ETolerance of Protein Folding to a Circular Permutation in a PDZ DomainDesolvation and development of specific hydrophobic core packing during Im7 folding.The folding of a family of three-helix bundle proteins: spectrin R15 has a robust folding nucleus, unlike its homologous neighbours.Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein.Behind the folding funnel diagram.The denatured state dictates the topology of two proteins with almost identical sequence but different native structure and function.Constrained proper sampling of conformations of transition state ensemble of protein folding.The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain.RNA molecules with conserved catalytic cores but variable peripheries fold along unique energetically optimized pathways.Equilibrium unfolding of the PDZ domain of β2-syntrophinFolding pathways of proteins with increasing degree of sequence identities but different structure and function.What lessons can be learned from studying the folding of homologous proteins?Morphogenesis of a protein: folding pathways and the energy landscape.Overview of protein folding mechanisms: experimental and theoretical approaches to probing energy landscapes.Sequence analysis on the information of folding initiation segments in ferredoxin-like fold proteins.Sequence-specific long range networks in PSD-95/discs large/ZO-1 (PDZ) domains tune their binding selectivity.Addressing the role of the α-helical extension in the folding of the third PDZ domain from PSD-95.Following easy slope paths on a free energy landscape: the case study of the Trp-cage folding mechanism.Allosteric activation of the Par-6 PDZ via a partial unfolding transition.Evolution of a protein folding nucleusAn oligomeric equilibrium intermediate as the precursory nucleus of globular and fibrillar supramacromolecular assemblies in a PDZ domain.Common features in the unfolding and misfolding of PDZ domains and beyond: the modulatory effect of domain swapping and extra-elements.Denaturants Alter the Flux Through Multiple Pathways in the Folding of PDZ Domain.Conserved nucleation sites reinforce the significance of Phi value analysis in protein-folding studies.Ratcheted molecular-dynamics simulations identify efficiently the transition state of protein folding.Frustration Sculpts the Early Stages of Protein Folding.Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.
P2860
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P2860
Comparison of successive transition states for folding reveals alternative early folding pathways of two homologous proteins.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Comparison of successive trans ...... ys of two homologous proteins.
@ast
Comparison of successive trans ...... ys of two homologous proteins.
@en
type
label
Comparison of successive trans ...... ys of two homologous proteins.
@ast
Comparison of successive trans ...... ys of two homologous proteins.
@en
prefLabel
Comparison of successive trans ...... ys of two homologous proteins.
@ast
Comparison of successive trans ...... ys of two homologous proteins.
@en
P2093
P2860
P50
P356
P1476
Comparison of successive trans ...... ys of two homologous proteins.
@en
P2093
Barbara Richter
Celestine N Chi
Lars Eklund
P2860
P304
19241-19246
P356
10.1073/PNAS.0804774105
P407
P50
P577
2008-11-25T00:00:00Z