The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol
about
Splice isoform estrogen receptors as integral transmembrane proteinsWhat's new in estrogen receptor action in the female reproductive tractDifferential ligand binding affinities of human estrogen receptor-α isoformsPredictive features of ligand-specific signaling through the estrogen receptorPulmonary Arterial Hypertension and the Sex Hormone Paradox.Mechanistic Pathways of Sex Differences in Cardiovascular Disease.Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.Endothelial estrogen receptor isoforms and cardiovascular diseaseNew selective estrogen and androgen receptor modulatorsPDE5 inhibitor efficacy is estrogen dependent in female heart disease.Update on estrogens and the skeletonMinireview: Extranuclear steroid receptors: roles in modulation of cell functions.Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in bone.Estradiol improves cardiovascular function through up-regulation of SOD2 on vascular wall.Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.From in vivo gene targeting of oestrogen receptors to optimization of their modulation in menopause.The role of estrogen receptor-α and its activation function-1 for growth plate closure in female mice.The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function.Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.Estrogen hormone physiology: reproductive findings from estrogen receptor mutant mice.Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.The role of activation functions 1 and 2 of estrogen receptor-α for the effects of estradiol and selective estrogen receptor modulators in male miceGeneral molecular biology and architecture of nuclear receptors.Sex steroids and bone health in men.SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice.Estradiol and tamoxifen regulate NRF-1 and mitochondrial function in mouse mammary gland and uterus.Membrane-initiated actions of estrogen on the endothelium.Prevention of obesity and insulin resistance by estrogens requires ERα activation function-2 (ERαAF-2), whereas ERαAF-1 is dispensable.The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumorsMinireview: dynamic structures of nuclear hormone receptors: new promises and challenges.Full antagonism of the estrogen receptor without a prototypical ligand side chain.Estrogen receptor actions on vascular biology and inflammation: implications in vascular pathophysiology.Extra-nuclear effects of estrogen on cortical bone in males require ERαAF-1.Estrogen Receptor-Dependent Regulation of Dendritic Cell Development and Function.Effects of estrogens and endocrine-disrupting chemicals on cell differentiation-survival-proliferation in brain: contributions of neuronal cell lines.The role of estrogen receptor α in the regulation of bone and growth plate cartilage.Androgen receptor modulators: a marriage of chemistry and biology.Cryptotanshinone and wogonin up-regulate eNOS in vascular endothelial cells via ERα and down-regulate iNOS in LPS stimulated vascular smooth muscle cells via ERβ.Nuclear and Membrane Actions of Estrogen Receptor Alpha: Contribution to the Regulation of Energy and Glucose Homeostasis.
P2860
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P2860
The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The transactivating function 1 ...... ve actions of 17beta-estradiol
@ast
The transactivating function 1 ...... ve actions of 17beta-estradiol
@en
type
label
The transactivating function 1 ...... ve actions of 17beta-estradiol
@ast
The transactivating function 1 ...... ve actions of 17beta-estradiol
@en
prefLabel
The transactivating function 1 ...... ve actions of 17beta-estradiol
@ast
The transactivating function 1 ...... ve actions of 17beta-estradiol
@en
P2093
P2860
P50
P356
P1476
The transactivating function 1 ...... ve actions of 17beta-estradiol
@en
P2093
Andrée Krust
Audrey Billon-Galés
Coralie Fontaine
Cédric Filipe
Gilles Flouriot
Marie-José Fouque
Pierre Chambon
P2860
P304
P356
10.1073/PNAS.0808742106
P407
P577
2009-02-02T00:00:00Z