RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.
about
The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.Spotlight on ixazomib: potential in the treatment of multiple myelomaThe B-cell receptor orchestrates environment-mediated lymphoma survival and drug resistance in B-cell malignanciesCell labeling approaches for fluorescence-based in vivo flow cytometryThe RhoA-ROCK pathway in the regulation of T and B cell responsesThe role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapyIn vivo flow cytometry: a horizon of opportunities.Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion eventsChanges in cell adhesivity and cytoskeleton-related proteins during imatinib-induced apoptosis of leukemic JURL-MK1 cells.The role of miR-451 in the switching between proliferation and migration in malignant glioma cells: AMPK signaling, mTOR modulation and Rac1 activation required.The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinibCo-expression of delta-catenin and RhoA is significantly associated with a malignant lung cancer phenotypeThe sialyltransferase ST3GAL6 influences homing and survival in multiple myelomaStromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophyRole of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells.Bayesian joint selection of genes and pathways: applications in multiple myeloma genomicsCD138-negative myeloma cells regulate mechanical properties of bone marrow stromal cells through SDF-1/CXCR4/AKT signaling pathwayMultiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype.Defining the role of TORC1/2 in multiple myeloma.SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction.P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironmentCXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features.Myeloma as a model for the process of metastasis: implications for therapyThe mesenchymal tumor microenvironment: a drug-resistant niche.Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a ∼ 125b cluster function by seed-targeting inhibitors in multiple myeloma cellsA CD138-independent strategy to detect minimal residual disease and circulating tumour cells in multiple myeloma.Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.Extracellular matrix protein Reelin promotes myeloma progression by facilitating tumor cell proliferation and glycolysis.Multidrug resistance in the chronic lymphoproliferative disorders.Environmental-mediated drug resistance: a target for multiple myeloma therapy.Molecular mechanisms of effectiveness of novel therapies in multiple myeloma.Molecularly targeted therapies in multiple myeloma3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma.Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib.PI3KCA plays a major role in multiple myeloma and its inhibition with BYL719 decreases proliferation, synergizes with other therapies and overcomes stroma-induced resistance.ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein.Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion.
P2860
Q24298336-DAD665E1-6BCB-4780-93D9-17D3E822EE6BQ26774440-1A337C50-FEDD-4281-8F37-ED4B4A28B2DEQ26822700-0633BF9D-6B61-47BE-825D-1331E31C22B3Q27693903-9543B72A-9CA5-41E4-ADDC-041E027FB8D8Q28066137-85EC97CA-B61E-4AD3-8C33-81AC35704B44Q28067724-FF1DDE44-3D77-4BA9-844B-04E355CAFAE5Q30454382-CA5EBF2F-A48F-4249-BAF1-471F7D4EE045Q33629153-88AEAC7E-2DB9-4BF1-82EE-B5EA9E06BCCEQ33689672-723A92BD-05EB-4BEF-AC01-1C4B4C5F7652Q33699443-F7AC5E6E-34DD-463F-9C0C-E3983EDFEE37Q33699564-F4CF9D60-5DBA-4324-B7B4-0A10EFD1C547Q33999971-F5003FEA-801D-4240-8913-F069E56CE37FQ34013386-EFF49CC6-74A3-45B9-8A53-22DF373F6612Q34028935-A3DBCC06-396C-4036-B141-B0C74F871D36Q34170367-37069817-706A-4C56-81EE-95CD5FEB5C53Q34279830-C8F558C2-EBC1-44A7-8487-791C40A29761Q34448984-3262DE0F-FF7F-41CE-94F7-6521BA4B7C83Q34662428-C4FF0089-5141-474E-A0C7-8B1138A5D841Q34898664-591FCE39-F484-41F3-8E17-6579F0687FD2Q34956540-BAE57838-79DF-4DE1-9FDF-EDC730A0D8CAQ35631315-CAC285BD-EED8-43D6-B6AF-47119607A280Q35732102-68E2FF5C-9465-4680-97A3-2BE9B6F2F493Q35776423-219E5166-C0E6-4811-96CD-75B970EE986CQ35994457-60A5353A-2B93-4BA3-BBB8-32C0CB715213Q36057606-97C84E65-7F5D-42C1-90F0-B9E6A95C4539Q36079800-AF91882F-51E5-41AB-8C04-6DCE345BE071Q36187755-5B3E5885-72A1-49EC-A69E-AEA954CA044AQ36189632-6E7A861A-AD55-4C7B-BD9F-F9E9F67BD643Q37032148-FDE00A1E-A7C4-4940-BC51-54447CA14F8DQ37331580-7B4DCBB7-868E-449B-8767-FB37D1CBA33EQ37721603-973F6802-9349-490A-9E03-1C7BD9134FD5Q37771031-4502FA96-38C8-4A67-8DA4-82BA5A1CD543Q37810085-38695407-550E-4B90-B908-D0216991A27FQ38035044-36CC3A5D-C514-4681-8433-421B1B0E5A86Q38211866-D8F37720-A6BF-4F08-A174-E43B49880CE8Q38832888-B7AA6BF8-1DC1-4818-8193-F010FA94168EQ38971845-071BD90A-9535-43C7-8F8E-C97522194987Q39036088-44C8D83D-12C0-4C67-9A38-C6E299B8D8B1Q39561478-7D38FC77-AE0F-4C0F-87F3-A54F3B57F79CQ39562168-197FF161-5EAB-45B4-89DC-899A234D48FB
P2860
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@ast
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@en
type
label
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@ast
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@en
prefLabel
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@ast
RhoA and Rac1 GTPases play maj ...... hemotaxis in multiple myeloma.
@en
P2093
P2860
P50
P1433
P1476
RhoA and Rac1 GTPases play maj ...... chemotaxis in multiple myeloma
@en
P2093
Abdel Kareem Azab
Barrett J Rollins
Brian Thompson
Charles P Lin
Costas M Pitsillides
Irene M Ghobrial
Judith M Runnels
Molly R Melhem
P2860
P304
P356
10.1182/BLOOD-2009-01-199281
P407
P577
2009-05-14T00:00:00Z