Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
about
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNAAutoinflammatory pustular neutrophilic diseasesHorror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragmentInflammasomes: too big to missUpdate on Pyrin Functions and Mechanisms of Familial Mediterranean FeverFamilial Mediterranean fever: current perspectivesBeyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescenceThe inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitisInitiation and perpetuation of NLRP3 inflammasome activation and assemblyDifferential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomesThe inflammasome NLRs in immunity, inflammation, and associated diseasesThe AIM2 inflammasome is critical for innate immunity to Francisella tularensisThe F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages.Activation of the pyrin inflammasome by intracellular Burkholderia cenocepaciaIdentification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death.Pyrin Modulates the Intracellular Distribution of PSTPIP1.Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.A splice variant of ASC regulates IL-1beta release and aggregates differently from intact ASC.Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasomeMonogenic IL-1 mediated autoinflammatory and immunodeficiency syndromes: finding the right balance in response to danger signalsMonogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis.Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levelsAdvances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.Inflammasomes and their activation.Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice.Immunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kindCrystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomersCaspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4.Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.Defective mitochondrial fission augments NLRP3 inflammasome activationTyrosine phosphatase inhibition induces an ASC-dependent pyroptosisRotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome ActivationNon-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activationThe Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.Autoinflammatory disease reloaded: a clinical perspective.
P2860
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P2860
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@ast
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@en
type
label
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@ast
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@en
prefLabel
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@ast
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@en
P2093
P2860
P921
P1433
P1476
Pyrin activates the ASC pyropt ...... toinflammatory PSTPIP1 mutants
@en
P2093
Christine Juliana
Emad S Alnemri
Je-Wook Yu
Jianghong Wu
Leobaldo Solorzano
Margaret McCormick
Pinaki Datta
Teresa Fernandes-Alnemri
ZhiJia Zhang
P2860
P304
P356
10.1016/J.MOLCEL.2007.08.029
P577
2007-10-01T00:00:00Z