The structure of the myosin VI motor reveals the mechanism of directionality reversal - Wikidata - awgldk - TriplyDB

The structure of the myosin VI motor reveals the mechanism of directionality reversal

The structure of the myosin VI motor reveals the mechanism of directionality reversal

http://www.wikidata.org/entity/Q30490997

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How are the cellular functions of myosin VI regulated within the cell?Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease Poorly understood aspects of striated muscle contraction Dense granule trafficking in Toxoplasma gondii requires a unique class 27 myosin and actin filaments Calcium can mobilize and activate myosin-VI Allosteric communication in myosin V: from small conformational changes to large directed movements The post-rigor structure of myosin VI and implications for the recovery stroke Myosin VI Dimerization Triggers an Unfolding of a Three-Helix Bundle in Order to Extend Its Reach Calmodulin Wraps around Its Binding Domain in the Plasma Membrane Ca2+ Pump Anchored by a Novel 18-1 Motif Insights into the Importance of Hydrogen Bonding in the γ-Phosphate Binding Pocket of Myosin: Structural and Functional Studies of Serine 236,Role of Insert-1 of Myosin VI in Modulating Nucleotide Affinity Structure of androcam supports specialized interactions with myosin VI Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning.Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel Strain Mediated Adaptation Is Key for Myosin Mechanochemistry: Discovering General Rules for Motor Activity Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular motor Adaptive evolution of the myo6 gene in old world fruit bats (family: pteropodidae)Lever-arm mechanics of processive myosins Functional characterization of the N-terminal region of myosin-2.Thirteen is enough: the myosins of Dictyostelium discoideum and their light chains.Biochemical and bioinformatic analysis of the myosin-XIX motor domain.Optical traps to study properties of molecular motors.The power stroke of myosin VI and the basis of reverse directionality.Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filaments.Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport Plus-end directed myosins accelerate actin filament sliding by single-headed myosin VI.Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanism Functional studies of individual myosin molecules.A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells Myosin individualized: single nucleotide polymorphisms in energy transduction.Mechanical coupling in myosin V: a simulation study Exome sequencing identifies a novel mutation in the MYH6 gene in a family with early-onset sinus node dysfunction, ventricular arrhythmias, and cardiac arrest Myosin isoform determines the conformational dynamics and cooperativity of actin filaments in the strongly bound actomyosin complex.A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.Reverse conformational changes of the light chain-binding domain of myosin V and VI processive motor heads during and after hydrolysis of ATP by small-angle X-ray solution scattering Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis Contribution of the myosin VI tail domain to processive stepping and intramolecular tension sensing.Structure of the light chain-binding domain of myosin V

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

http://www.wikidata.org/entity/Q30490997

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2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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The structure of the myosin VI motor reveals the mechanism of directionality reversal

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Amber L Wells

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Anne Houdusse

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Carl A Morris

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Christopher M Yengo

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H Lee Sweeney

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Julie Ménétrey

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P2860

Myosin VI is an actin-based motor that moves backwards

Three myosin V structures delineate essential features of chemo-mechanical transduction

Myosin VI is a processive motor with a large step size

A millennial myosin census

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head

Three conformational states of scallop myosin S1

A structural state of the myosin V motor without bound nucleotide

A closed compact structure of native Ca(2+)-calmodulin

Automated protein model building combined with iterative structure refinement

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