Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance - Wikidata - awgldk - TriplyDB

Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance

Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance

http://www.wikidata.org/entity/Q30492656

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A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.3p-- syndrome defines a hearing loss locus in 3p25.3 The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss.Rapid turnover of stereocilia membrane proteins: evidence from the trafficking and mobility of plasma membrane Ca(2+)-ATPase 2.Expression of epithelial calcium transport system in rat cochlea and vestibular labyrinth.Early growth response protein 1 regulates promoter activity of α-plasma membrane calcium ATPase 2, a major calcium pump in the brain and auditory system.The development, distribution and density of the plasma membrane calcium ATPase 2 calcium pump in rat cochlear hair cells.Two ENU-induced alleles of Atp2b2 cause deafness in mice.Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications.The novel PMCA2 pump mutation Tommy impairs cytosolic calcium clearance in hair cells and links to deafness in mice.The micromachinery of mechanotransduction in hair cells.Loss of cochlear HCO3- secretion causes deafness via endolymphatic acidification and inhibition of Ca2+ reabsorption in a Pendred syndrome mouse model.Steady-state adaptation of mechanotransduction modulates the resting potential of auditory hair cells, providing an assay for endolymph [Ca2+].Scotopic visual signaling in the mouse retina is modulated by high-affinity plasma membrane calcium extrusion.Strain background effects and genetic modifiers of hearing in mice.Regulation of cellular calcium in vestibular supporting cells by otopetrin 1 Expression, functional, and structural analysis of proteins critical for otoconia development Apical localization of PMCA2w/b is enhanced in terminally polarized MDCK cells Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.The gastric H,K-ATPase in stria vascularis contributes to pH regulation of cochlear endolymph but not to K secretion.The resting transducer current drives spontaneous activity in prehearing mammalian cochlear inner hair cells Splice-site A choice targets plasma-membrane Ca2+-ATPase isoform 2 to hair bundles.Supporting sensory transduction: cochlear fluid homeostasis and the endocochlear potential.Ca2+ signaling in the inner ear.Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers.Stria vascularis and vestibular dark cells: characterisation of main structures responsible for inner-ear homeostasis, and their pathophysiological relations.Usher proteins in inner ear structure and function Calcium pumps in health and disease.Ca2+ homeostasis defects and hereditary hearing loss.Neuronal calcium sensor-1 gene ncs-1a is essential for semicircular canal formation in zebrafish inner ear.Changes in cochlear PMCA2 expression correlate with the maturation of auditory sensitivity.Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea.Evidence for a role of plasma membrane calcium pumps in neurodegenerative disease: Recent developments.

P2860

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P2860

Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance

http://www.wikidata.org/entity/Q30492656

description

2004 nî lūn-bûn

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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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Low endolymph calcium concentr ...... endolymph calcium maintenance

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Low endolymph calcium concentr ...... endolymph calcium maintenance

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type

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Low endolymph calcium concentr ...... endolymph calcium maintenance

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Low endolymph calcium concentr ...... endolymph calcium maintenance

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Low endolymph calcium concentr ...... endolymph calcium maintenance

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Low endolymph calcium concentr ...... endolymph calcium maintenance

@en

P2093

Adelaida G Filoteo

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Bruce L Tempel

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J David Wood

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John T Penniston

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Sara J Muchinsky

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P2860

Ion transport in guinea pig cochlea. I. Potassium and sodium transport

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice

mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw)

The MyoD family and myogenesis: redundancy, networks, and thresholds

Plasma membrane Ca2+-ATPase isoform 2a is the PMCA of hair bundles.

Voltage dependence of adaptation and active bundle movement in bullfrog saccular hair cells.

Ionic basis of the receptor potential in a vertebrate hair cell.

Very low calcium content of cochlear endolymph, an extracellular fluid.

Mechano-electrical transduction currents in isolated vestibular hair cells of the chick.

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2

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5

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