Conversion of the allosteric transition of GroEL from concerted to sequential by the single mutation Asp-155 -> Ala.
about
Perturbation-based Markovian transmission model for probing allosteric dynamics of large macromolecular assembling: a study of GroEL-GroESCrystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 A resolutionDynamics of allosteric transitions in GroEL.Allostery and cooperativity revisited.Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner.Football- and bullet-shaped GroEL-GroES complexes coexist during the reaction cycle.Spontaneous conformational changes in the E. coli GroEL subunit from all-atom molecular dynamics simulations.The Hsp60-(p.V98I) mutation associated with hereditary spastic paraplegia SPG13 compromises chaperonin function both in vitro and in vivo.Markov propagation of allosteric effects in biomolecular systems: application to GroEL-GroES.Concerted release of substrate domains from GroEL by ATP is demonstrated with FRET.Sequential ATP-induced allosteric transitions of the cytoplasmic chaperonin containing TCP-1 revealed by EM analysis.The versatile mutational "repertoire" of Escherichia coli GroEL, a multidomain chaperonin nanomachine.
P2860
Q27335329-176B94C2-7696-4D99-96F1-BA043F5E5FD4Q27679114-7AC9DE98-E124-4375-9EAA-9F40F6691F4CQ30478627-7A093412-E22C-4F0B-9FAD-3044AA3993E5Q34786984-4E8F597B-B400-46BE-932B-889FA057E3F2Q35652550-F81410D3-7D21-4574-A545-51E14EA68C39Q35676628-F6DD9A7B-706C-4C9E-9FBA-626B541DE4F9Q35963381-10724A21-2E29-4F32-BBB6-406887F9DB16Q40447118-2787E5C8-F818-425F-9AA8-9BA0DDB6ED6CQ40512092-D9191600-B554-417F-9492-27BA61B01F4FQ41711174-8BB4633D-3D69-4A47-9B15-14061E5F6769Q45254396-27401AB8-B3DC-4CEA-98D5-E11969E117A1Q47308168-414B18C5-CA36-4E92-B7A8-C6CBA534FA94
P2860
Conversion of the allosteric transition of GroEL from concerted to sequential by the single mutation Asp-155 -> Ala.
description
2003 nî lūn-bûn
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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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name
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@ast
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@en
type
label
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@ast
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@en
prefLabel
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@ast
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@en
P2093
P2860
P356
P1476
Conversion of the allosteric t ...... ingle mutation Asp-155 -> Ala.
@en
P2093
Amnon Horovitz
Dalia Rivenzon-Segal
Oded Danziger
P2860
P304
13797-13802
P356
10.1073/PNAS.2333925100
P407
P577
2003-11-13T00:00:00Z