Tau isoform regulation is region- and cell-specific in mouse brain. - Wikidata - awgldk - TriplyDB

Tau isoform regulation is region- and cell-specific in mouse brain.

Tau isoform regulation is region- and cell-specific in mouse brain.

http://www.wikidata.org/entity/Q30493882

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Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion Temperature and toxic Tau in Alzheimer's disease: new insights Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes Tau-mediated synaptic damage in Alzheimer's disease Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.Roles of tau protein in health and disease.Acetylation of tau inhibits its degradation and contributes to tauopathy Physiological transgene regulation and functional complementation of a neurological disease gene deficiency in neurons Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia.Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease.Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus.Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells.Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β.Truncation of tau at E391 promotes early pathologic changes in transgenic mice Regulation of human MAPT gene expression.Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion.Evolution of neurodegeneration.Transcriptomic changes in brain development.HIV-1-Tat Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A Kinase.The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells.Gene Therapy Models of Alzheimer's Disease and Other Dementias.Brain-derived neurotrophic factor and TrkB expression in the "oldest-old," the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease.Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau Molecular nexopathies: a new paradigm of neurodegenerative disease.Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration Anti-amyloid beta to tau - based immunization: Developments in immunotherapy for Alzheimer disease.Tau mis-splicing in the pathogenesis of neurodegenerative disorders.Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits.Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau.The Effects of SIRT1 on Alzheimer's Disease Models.

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P2860

Tau isoform regulation is region- and cell-specific in mouse brain.

http://www.wikidata.org/entity/Q30493882

description

2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

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2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

@wuu

name

Tau isoform regulation is region- and cell-specific in mouse brain.

@ast

Tau isoform regulation is region- and cell-specific in mouse brain.

@en

type

label

Tau isoform regulation is region- and cell-specific in mouse brain.

@ast

Tau isoform regulation is region- and cell-specific in mouse brain.

@en

prefLabel

Tau isoform regulation is region- and cell-specific in mouse brain.

@ast

Tau isoform regulation is region- and cell-specific in mouse brain.

@en

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The Journal of Comparative Neurology

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Tau isoform regulation is region- and cell-specific in mouse brain

@en

P2093

Elena Korvatska

http://www.w3.org/2001/XMLSchema#string

Gerard D Schellenberg

http://www.w3.org/2001/XMLSchema#string

Ian D'Souza

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Linda Robinson

http://www.w3.org/2001/XMLSchema#string

Lynne Greenup

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Pamela McMillan

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Parvoneh Poorkaj

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Zana Evstafjeva

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P2860

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain

Tau protein binds to microtubules through a flexible array of distributed weak sites

Phage annealing proteins promote oligonucleotide-directed mutagenesis in Escherichia coli and mouse ES cells

Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

A new logic for DNA engineering using recombination in Escherichia coli

Neurodegenerative tauopathies

The microtubule binding domain of tau protein.

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788-803

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scholarly article

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10.1002/CNE.21867

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P433

6

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511

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James B Leverenz

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2008-12-01T00:00:00Z

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23388212

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18925637

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2845852

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