Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water.
about
New insights into the mechanisms of action of aspirin and its use in the prevention and treatment of arterial and venous thromboembolismAn approach to quantifying 3D responses of cells to extreme strainUsing molecular mechanics to predict bulk material properties of fibronectin fibersFunctional impact of oxidative posttranslational modifications on fibrinogen and fibrin clots.High sensitivity micro-elastometry: applications in blood coagulopathy.Towards the understanding of cytoskeleton fluidisation-solidification regulation.Force-dependent polymorphism in type IV pili reveals hidden epitopes.The mechanical properties of single fibrin fibers.Mechanism of fibrin(ogen) forced unfolding.Strain history dependence of the nonlinear stress response of fibrin and collagen networks.Strain tunes proteolytic degradation and diffusive transport in fibrin networksEstimating the 3D pore size distribution of biopolymer networks from directionally biased data.Impact of saccharides on the drying kinetics of agarose gels measured by in-situ interferometry.Discovery through the computational microscope.Stiffening of individual fibrin fibers equitably distributes strain and strengthens networks.Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging.Control of perfusable microvascular network morphology using a multiculture microfluidic systemComposition of coronary thrombus in acute myocardial infarction.Concentration independent modulation of local micromechanics in a fibrin gel.Structural basis for the nonlinear mechanics of fibrin networks under compression.Probabilistic modeling and analysis of the effects of extra-cellular matrix density on the sizes, shapes, and locations of integrin clusters in adherent cells.α-α Cross-links increase fibrin fiber elasticity and stiffnessExtending vaterite microviscometry to ex vivo blood vessels by serial calibrationOrder statistics theory of unfolding of multimeric proteins.Evidence that αC region is origin of low modulus, high extensibility, and strain stiffening in fibrin fibersThe molecular origins of the mechanical properties of fibrin.Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activationMolecular mechanisms affecting fibrin structure and stability.A protein from Aloe vera that inhibits the cleavage of human fibrin(ogen) by plasmin.Elastic behavior and platelet retraction in low- and high-density fibrin gels.Hindered dissolution of fibrin formed under mechanical stressProtein unfolding accounts for the unusual mechanical behavior of fibrin networks.Micromechanical poroelastic finite element and shear-lag models of tendon predict large strain dependent Poisson's ratios and fluid expulsion under tensile loading.Microbuckling of fibrin provides a mechanism for cell mechanosensingBlood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization: Biophysical regulation of hematopoietic differentiation and trafficking.The α-helix to β-sheet transition in stretched and compressed hydrated fibrin clotsUniversal behavior of hydrogels confined to narrow capillariesKinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the bloodMechanical transition from α-helical coiled coils to β-sheets in fibrin(ogen)Correlating confocal microscopy and atomic force indentation reveals metastatic cancer cells stiffen during invasion into collagen I matrices
P2860
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P2860
Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@ast
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@en
type
label
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@ast
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@en
prefLabel
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@ast
Multiscale mechanics of fibrin ...... n unfolding and loss of water.
@en
P2093
P2860
P356
P1433
P1476
Multiscale mechanics of fibrin ...... in unfolding and loss of water
@en
P2093
John W Weisel
Prashant K Purohit
Rustem I Litvinov
P2860
P304
P356
10.1126/SCIENCE.1172484
P407
P577
2009-08-01T00:00:00Z