Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling
about
The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neuronsRole of Bassoon and Piccolo in Assembly and Molecular Organization of the Active ZoneThe dynamic architecture of photoreceptor ribbon synapses: cytoskeletal, extracellular matrix, and intramembrane proteinsSustaining rapid vesicular release at active zones: potential roles for vesicle tetheringThe cochlea as an independent neuroendocrine organ: expression and possible roles of a local hypothalamic-pituitary-adrenal axis-equivalent signaling systemIntegration of multiscale dendritic spine structure and function data into systems biology modelsComplex network analysis of CA3 transcriptome reveals pathogenic and compensatory pathways in refractory temporal lobe epilepsyRab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zonesDual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.New insights into cochlear sound encodingHippocampal CA3 transcriptome signature correlates with initial precipitating injury in refractory mesial temporal lobe epilepsySynaptic activity controls localization and function of CtBP1 via binding to Bassoon and PiccoloBassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradationHair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.Cochlear hair cells: The sound-sensing machines.Relating structure and function of inner hair cell ribbon synapses.Morphological and physiological development of auditory synapses.Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.Ouabain-induced cochlear nerve degeneration: synaptic loss and plasticity in a mouse model of auditory neuropathy.Quantitative analysis of ribbons, vesicles, and cisterns at the cat inner hair cell synapse: correlations with spontaneous rate.Developmental acquisition of a rapid calcium-regulated vesicle supply allows sustained high rates of exocytosis in auditory hair cells.Modes and regulation of endocytic membrane retrieval in mouse auditory hair cellsA Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearingTransmitter release from cochlear hair cells is phase locked to cyclic stimuli of different intensities and frequencies.Synaptic profiles during neurite extension, refinement and retraction in the developing cochleaThe cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma.Recovery from short-term depression and facilitation is ultrafast and Ca2+ dependent at auditory hair cell synapses.EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cellsZebrafish Cacna1fa is required for cone photoreceptor function and synaptic ribbon formationA new probe for super-resolution imaging of membranes elucidates trafficking pathwaysRab Interacting Molecules 2 and 3 Directly Interact with the Pore-Forming CaV1.3 Ca2+ Channel Subunit and Promote Its Membrane Expression.Conical tomography of a ribbon synapse: structural evidence for vesicle fusion.Enlargement of Ribbons in Zebrafish Hair Cells Increases Calcium Currents But Disrupts Afferent Spontaneous Activity and Timing of Stimulus Onset.Role of exercise in maintaining the integrity of the neuromuscular junction.In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses.Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses.Active zone protein Bassoon co-localizes with presynaptic calcium channel, modifies channel function, and recovers from aging related loss by exercise.Cell-specific STORM super-resolution imaging reveals nanoscale organization of cannabinoid signaling.Properties of ribbon and non-ribbon release from rod photoreceptors revealed by visualizing individual synaptic vesiclesRegulation of presynaptic anchoring of the scaffold protein Bassoon by phosphorylation-dependent interaction with 14-3-3 adaptor proteins.
P2860
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P2860
Bassoon and the synaptic ribbon organize Ca²+ channels and vesicles to add release sites and promote refilling
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@ast
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@en
type
label
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@ast
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@en
prefLabel
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@ast
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@en
P2093
P2860
P50
P1433
P1476
Bassoon and the synaptic ribbo ...... se sites and promote refilling
@en
P2093
Andreas Neef
Benjamin Harke
Darina Khimich
Dietmar Riedel
Eckart D Gundelfinger
Keith E Bryan
M Charles Liberman
Nicola Strenzke
Tina Pangršič
P2860
P304
P356
10.1016/J.NEURON.2010.10.027
P407
P577
2010-11-01T00:00:00Z