Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia. - Wikidata - awgldk - TriplyDB

Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.

Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.

http://www.wikidata.org/entity/Q30498141

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Lean heart: Role of leptin in cardiac hypertrophy and metabolism Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes Multifaceted interplay among mediators and regulators of intestinal glucose absorption: potential impacts on diabetes research and treatment Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy Does oral glutamine improve insulin sensitivity in adolescents with type 1 diabetes?The role of leptin in glucose homeostasis.Neuronal control of peripheral insulin sensitivity and glucose metabolism An acute method to test leptin responsiveness in rats.Thyroid hormone regulation of metabolism Neurobiology of food intake in health and disease.Leptin, GABA, and glucose control Leptin signaling.Control of hepatic glucose metabolism by islet and brain.Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes.Cyclic AMP sensor EPAC proteins and energy homeostasis.Exercise, energy intake, glucose homeostasis, and the brain Gut-brain mechanisms controlling glucose homeostasis.Subcutaneous administration of leptin normalizes fasting plasma glucose in obese type 2 diabetic UCD-T2DM rats.Glucose effectiveness in obese children: relation to degree of obesity and dysglycemia.Leptin in human physiology and pathophysiology.Brain-mediated antidiabetic, anorexic, and cardiovascular actions of leptin require melanocortin-4 receptor signaling.Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling.Leptin and the central nervous system control of glucose metabolism.Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice Minireview: CNS Mechanisms of Leptin Action.The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux Leptin, diabetes, and the brain Leptin therapy, insulin sensitivity, and glucose homeostasis.Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle.The role of leptin in the control of insulin-glucose axis.Leptin acts in the brain to influence hypoglycemic counterregulation: disparate effects of acute and recurrent hypoglycemia on glucagon release.In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production.Functional identification of a neurocircuit regulating blood glucose.Leptin administration enhances islet transplant performance in diabetic mice.

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Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia.

http://www.wikidata.org/entity/Q30498141

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

Leptin activates a novel CNS m ...... severe diabetic hyperglycemia.

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Leptin activates a novel CNS m ...... severe diabetic hyperglycemia.

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type

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Leptin activates a novel CNS m ...... severe diabetic hyperglycemia.

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Leptin activates a novel CNS m ...... severe diabetic hyperglycemia.

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Leptin activates a novel CNS m ...... severe diabetic hyperglycemia.

@en

P2093

Brent E Wisse

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David A Sarruf

http://www.w3.org/2001/XMLSchema#string

Gerald J Taborsky

http://www.w3.org/2001/XMLSchema#string

Gregory J Morton

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Jonathan D Fischer

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Jonathan P German

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Joshua P Thaler

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Michael W Schwartz

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Miles E Matsen

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Shinsuke Oh-I

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P2860

Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility

Role of leptin in the neuroendocrine response to fasting

Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.

Leptin deficiency causes insulin resistance induced by uncontrolled diabetes.

The effect of experimental insulin deficiency on glucagon secretion.

Glucocorticoids and hepatic glycogen metabolism.

Hypothalamic K(ATP) channels control hepatic glucose production.

A brain-liver circuit regulates glucose homeostasis.

Splanchnic regulation of glucose production.

Making insulin-deficient type 1 diabetic rodents thrive without insulin.

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394-404

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10.1210/EN.2010-0890

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2

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152

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2010-12-15T00:00:00Z

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21159853

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