Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. - Wikidata - awgldk - TriplyDB

Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

http://www.wikidata.org/entity/Q30499402

about

TGF-β/Smad signaling in renal fibrosis Smads as therapeutic targets for chronic kidney disease Polarity of response to transforming growth factor-beta1 in proximal tubular epithelial cells is regulated by beta-catenin Role of the TGF-β/BMP-7/Smad pathways in renal diseases Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems.Explorations of high-intensity therapeutic ultrasound and microbubble-mediated gene delivery in mouse liver Delivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasis Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery Targeted renal therapies through microbubbles and ultrasound.Treatment of established peritoneal fibrosis by gene transfer of Smad7 in a rat model of peritoneal dialysis.Physical approaches for nucleic acid delivery to liver.Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis.miR-192 mediates TGF-beta/Smad3-driven renal fibrosis.Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro.The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.Role of Sema4C in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy Therapeutic targets for treating fibrotic kidney diseases Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29 Silencing of hypoxia-inducible factor-1α gene attenuated angiotensin II-induced renal injury in Sprague-Dawley rats.Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice.Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie's plaque.Advances in Gene Delivery Systems.Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis.Smad7 protects against chronic aristolochic acid nephropathy in mice.Cdc42-interacting protein-4 promotes TGF-Β1-induced epithelial-mesenchymal transition and extracellular matrix deposition in renal proximal tubular epithelial cells.Transforming growth factor-β, bioenergetics, and mitochondria in renal disease Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis.Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs.Gene therapy targeting kidney diseases: routes and vehicles.Therapeutic potential of TGF-beta inhibition in chronic renal failure.Gene therapy progress and prospects: ultrasound for gene transfer.Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease Inhibition of hyperhomocysteinemia-induced inflammasome activation and glomerular sclerosis by NLRP3 gene deletion.Targeting c-fms kinase attenuates chronic aristolochic acid nephropathy in mice Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism.Transforming growth factor-beta and the glomerular filtration barrier.

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P2860

Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

http://www.wikidata.org/entity/Q30499402

description

2005 nî lūn-bûn

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2005 թուականի Մարտին հրատարակուած գիտական յօդուած

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2005 թվականի մարտին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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type

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Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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prefLabel

Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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Ultrasound-microbubble-mediate ...... ibrosis in rat remnant kidney.

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The American Journal of Pathology

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Ultrasound-microbubble-mediate ...... fibrosis in rat remnant kidney

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P2093

Chun-Cheng Hou

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David Sheikh-Hamad

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Ping Fu

http://www.w3.org/2001/XMLSchema#string

Tso-Hsiao Chen

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Wansheng Wang

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Xiao R Huang

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P2860

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells

Inhibitory smads and tgf-Beta signaling in glomerular cells

Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice

Renoprotective benefits of RAS inhibition: from ACEI to angiotensin II antagonists.

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

Angiotensin II, TGF-beta and renal fibrosis.

TGF-beta signaling in renal disease.

Prevention of hypertension and its complications: theoretical basis and guidelines for treatment.

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