Essential role for Abi1 in embryonic survival and WAVE2 complex integrity - Wikidata - awgldk - TriplyDB

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

http://www.wikidata.org/entity/Q30499934

about

Spectrin-based skeleton as an actor in cell signaling Phosphoregulation of the WAVE regulatory complex and signal integration WAVE2 regulates epithelial morphology and cadherin isoform switching through regulation of Twist and Abl Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma.The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions.Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia.Expression and Y435-phosphorylation of Abelson interactor 1 (Abi1) promotes tumour cell adhesion, extracellular matrix degradation and invasion by colorectal carcinoma cells.Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity.Membrane protrusion powers clathrin-independent endocytosis of interleukin-2 receptor Loss of Wave1 gene defines a subtype of lethal prostate cancer Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation.Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton.Abelson interactor 1 (ABI1) and its interaction with Wiskott-Aldrich syndrome protein (wasp) are critical for proper eye formation in Xenopus embryos.CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila.New Abelson interactor-1 (Abi-1)-driven mechanism of acquired drug resistance.Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia.[Abelson interactor 1 (Abi1) in colorectal cancer. From synaptic plasticity to tumor cell migration].

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Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

http://www.wikidata.org/entity/Q30499934

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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type

label

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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prefLabel

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

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PNAS.1016811108

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

@en

P2093

Anna Chorzalska

http://www.w3.org/2001/XMLSchema#string

Janet A Sawicki

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Kathrin I Ladwein

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Leszek Kotula

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Patrycja M Dubielecka

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Xiaoling Xiong

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P2860

Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia

Structure and control of the actin regulatory WAVE complex

Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth

Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton

Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells

Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse

Differential regulation of macropinocytosis by Abi1/Hssh3bp1 isoforms

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7022-7027

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scholarly article

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10.1073/PNAS.1016811108

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17

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108

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Kathryn V. Anderson

Klemens Rottner

Theresia Stradal

Isabelle Migeotte

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2011-04-11T00:00:00Z

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51041578

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