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Algorithms for the diagnosis and treatment of restless legs syndrome in primary careA single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study.Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1One year open-label safety and efficacy trial with rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome.Blood cis-eQTL analysis fails to identify novel association signals among sub-threshold candidates from genome-wide association studies in restless legs syndrome.Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patchFamily-based association study of the restless legs syndrome loci 2 and 3 in a European population.Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.The REM sleep behavior disorder screening questionnaire--a new diagnostic instrument.Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome.Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice.Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study.DTI and VBM reveal white matter changes without associated gray matter changes in patients with idiopathic restless legs syndrome.Normal regional brain iron concentration in restless legs syndrome measured by MRIState of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome.Pathophysiological concepts of restless legs syndrome.Assessment of restless legs syndrome--methodological approaches for use in practice and clinical trials.Genetics of restless legs syndrome (RLS): State-of-the-art and future directions.Update of the pathophysiology of the restless-legs-syndrome.Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13.Restless Legs Syndrome (RLS) and Parkinson's disease (PD)-related disorders or different entities?Health-related quality of life and economic burden in patients with restless legs syndrome.Continuous sleep EEG monitoring in PD patients with and without sleep attacks.Validation of the Augmentation Severity Rating Scale (ASRS): a multicentric, prospective study with levodopa on restless legs syndrome.Predictors of freezing in Parkinson's disease: a survey of 6,620 patients.Rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome: a randomized, placebo-controlled polysomnographic study.Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: a peripheral biomarker for early Parkinson's disease?Normal dopaminergic and serotonergic metabolites in cerebrospinal fluid and blood of restless legs syndrome patients.Low-dose pramipexole in the management of restless legs syndrome. An open label trial.Predictors of sudden onset of sleep in Parkinson's disease.Patch application of the dopamine agonist rotigotine to patients with moderate to advanced stages of restless legs syndrome: a double-blind, placebo-controlled pilot study.PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial.Daytime sleep latency in medication-matched Parkinsonian patients with and without sudden onset of sleep.Preprohypocretin polymorphisms in Parkinson disease patients reporting "sleep attacks".Assessment of idiopathic rapid-eye-movement sleep behavior disorder by transcranial sonography, olfactory function test, and FP-CIT-SPECT.Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease.The PD-associated alpha-synuclein promoter Rep1 allele 2 shows diminished frequency in restless legs syndrome.Diagnostic value of the REM sleep behavior disorder screening questionnaire in Parkinson's disease.Erratum to: Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case-control study.
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Karin Stiasny-Kolster
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