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ImmunoChip study implicates antigen presentation to T cells in narcolepsyMultiple common variants for celiac disease influencing immune gene expressionEvolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infectionNewly identified genetic risk variants for celiac disease related to the immune responseCoeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signallingGenome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritisMeta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared lociA meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac diseaseGenetics of rheumatoid arthritis contributes to biology and drug discoveryContrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity.Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cellsHigh-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry.Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac diseaseVariants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.Complex nature of SNP genotype effects on gene expression in primary human leucocytesPotential celiac patients: a model of celiac disease pathogenesis.Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLACommon variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease.Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulationChromatin marks identify critical cell types for fine mapping complex trait variants.A genetic perspective on coeliac disease.Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays.Immunogenomic approaches to understand the function of immune disease variants.Exome sequencing in a family segregating for celiac disease.Common and different genetic background for rheumatoid arthritis and coeliac disease.Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis.Enhancers looping to target genes.Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease.Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease.Genomic profiling of T cell activation reveals dependency of memory T cells on CD28 costimulationDisentangling effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex trait lociThe single-cell eQTLGen consortiumChromatin activity at GWAS loci identifies T cell states driving complex immune diseasesImmunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac diseaseSingle-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
P50
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P50
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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Gosia Trynka
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P108
P106
P21
P31
P496
0000-0002-6955-9529