A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
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Signaling in Effector Lymphocytes: Insights toward Safer ImmunotherapyCell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionPKC-Theta in Regulatory and Effector T-cell FunctionsNF-κB, the first quarter-century: remarkable progress and outstanding questionsCell polarisation and the immunological synapseThe Novel PKCθ from Benchtop to ClinicMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseDistinct Roles of Cytoskeletal Components in Immunological Synapse Formation and Directed Secretion.Actin nucleation at the centrosome controls lymphocyte polarity.Diacylglycerol kinase α establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapseDiacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell PolarityThe Immunomodulatory Functions of Diacylglycerol Kinase ζDiacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in CancerCentrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin IIWASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts.Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins.Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1.The variable hinge region of novel PKCs determines localization to distinct regions of the immunological synapseLymphocyte polarity, the immunological synapse and the scope of biological analogy.Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse.NHE3 phosphorylation via PKCη marks the polarity and orientation of directionally migrating cellsFrom lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cellseNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.The emerging role of protein kinase Cθ in cytoskeletal signaling.Pseudomonas aeruginosa Activates PKC-Alpha to Invade Middle Ear Epithelial Cells.Diacylglycerol kinases: regulated controllers of T cell activation, function, and development.In and out of the bull's eye: protein kinase Cs in the immunological synapse.Role of diacylglycerol kinases in T cell development and function.Regulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and FunctionVav1-phospholipase C-γ1 (Vav1-PLC-γ1) pathway initiated by T cell antigen receptor (TCRγδ) activation is required to overcome inhibition by ubiquitin ligase Cbl-b during γδT cell cytotoxicity.Lipid-based patterning of the immunological synapseThe yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes.The role of protein kinase cη in T cell biologyMicrotubule-organizing center polarity and the immunological synapse: protein kinase C and beyondThe role of the cytoskeleton at the immunological synapse.Orchestrating cytoskeleton and intracellular vesicle traffic to build functional immunological synapses.The actin-driven spatiotemporal organization of T-cell signaling at the system scale.The newly found functions of MTOC in immunological response.
P2860
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P2860
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@ast
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@en
type
label
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@ast
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@en
prefLabel
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@ast
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@en
P2093
P2860
P356
P1433
P1476
A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.
@en
P2093
Emily J Quann
Grégoire Altan-Bonnet
Morgan Huse
P2860
P304
P356
10.1038/NI.2033
P407
P577
2011-05-22T00:00:00Z