Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1. - Wikidata - awgldk - TriplyDB

Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1.

Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1.

http://www.wikidata.org/entity/Q30502964

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Subdominant Outer Membrane Antigens in Anaplasma marginale: Conservation, Antigenicity, and Protective Capacity Using Recombinant Protein Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine Malaria Parasites: The Great Escape Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria Peripheral blood cell signatures of Plasmodium falciparum infection during pregnancy Functional antibodies against VAR2CSA in nonpregnant populations from colombia exposed to Plasmodium falciparum and Plasmodium vivax.Submicroscopic infections with Plasmodium falciparum during pregnancy and their association with circulating cytokine, chemokine, and cellular profiles.The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates.Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites.Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites Variable VlsE is critical for host reinfection by the Lyme disease spirochete.The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site Malaria and immunity during pregnancy and postpartum: a tale of two species α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes.Evasion of Immunity to Plasmodium falciparum: Rosettes of Blood Group A Impair Recognition of PfEMP1.Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain.Genetic Resistance to Malaria Is Associated With Greater Enhancement of Immunoglobulin (Ig)M Than IgG Responses to a Broad Array of Plasmodium falciparum Antigens.Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 Variants per Genome Can Bind IgM via Its Fc Fragment Fcμ Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding.In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription.Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6ℇ-FCR3 of the Plasmodium falciparum VAR2CSA protein.Antibodies to Escherichia coli-expressed C-terminal domains of Plasmodium falciparum variant surface antigen 2-chondroitin sulfate A (VAR2CSA) inhibit binding of CSA-adherent parasites to placental tissue.Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites.Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine.The immunological balance between host and parasite in malaria.Does antibody binding to diverse antigens predict future infection?Variant surface antigens of Plasmodium falciparum and their roles in severe malaria.Investigating the function of Fc-specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting.The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria.Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure.Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria.Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.Role of the VlsE Lipoprotein in Immune Avoidance by the Lyme Disease Spirochete Borrelia burgdorferi.CD28 deficiency leads to accumulation of germinal-center independent IgM+ experienced B cells and to production of protective IgM during experimental malaria

P2860

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P2860

Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1.

http://www.wikidata.org/entity/Q30502964

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2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

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Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

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type

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Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

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Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

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Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

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Proceedings of the National Academy of Sciences of the United States of America

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Evasion of immunity to Plasmod ...... rocyte surface-exposed PfEMP1.

@en

P2093

Michael B Dalgaard

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Michael F Ofori

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Suzan T Pleman

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P2860

Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum

Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

Surface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

IgM, Fc mu Rs, and malarial immune evasion

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias.

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies.

Plasmodium falciparum rosette formation is uncommon in isolates from pregnant women.

The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains

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12485-12490

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10.1073/PNAS.1103708108

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30

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108

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Richard J. Pleass

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2011-07-11T00:00:00Z

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51483554

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21746929

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Plasmodium falciparum

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3145728

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