about
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humansDeciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous SystemSelective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunityHerpes simplex virus encephalitis in human UNC-93B deficiencyIgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patientsHGCS: an online tool for prioritizing disease-causing gene variants by biological distanceHuman TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis.Inherited MST1 deficiency underlies susceptibility to EV-HPV infectionsInfectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiencyTLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk.Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies.A partial form of recessive STAT1 deficiency in humans.Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation.NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiencyInborn errors of anti-viral interferon immunity in humans.Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections.Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3.Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhoodThe human gene damage index as a gene-level approach to prioritizing exome variants.Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.Host genetics of severe influenza: from mouse Mx1 to human IRF7Parsing the Interferon Transcriptional Network and Its Disease AssociationsTLR3 immunity to infection in mice and humansThe human gene connectome as a map of short cuts for morbid allele discovery.The proteome of Toll-like receptor 3-stimulated human immortalized fibroblasts: implications for susceptibility to herpes simplex virus encephalitisHuman primary immunodeficiencies of type I interferons.Human Toll-like receptor-dependent induction of interferons in protective immunity to viruses.Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans.EVER2 deficiency is associated with mild T-cell abnormalities.From infectious diseases to primary immunodeficiencies.Revisiting human primary immunodeficiencies.Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense.Primary immunodeficiencies of protective immunity to primary infections.Mendelian predisposition to herpes simplex encephalitis.Addressing diagnostic challenges in primary immunodeficiencies: laboratory evaluation of Toll-like receptor- and NF-κB-mediated immune responses.Human TBK1: A Gatekeeper of NeuroinflammationCleaved/associated TLR3 represents the primary form of the signaling receptor.TLR3 deficiency in patients with herpes simplex encephalitis.
P50
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Shen-Ying Zhang
@ast
Shen-Ying Zhang
@en
Shen-Ying Zhang
@es
Shen-Ying Zhang
@fr
Shen-Ying Zhang
@nl
Shen-Ying Zhang
@sl
type
label
Shen-Ying Zhang
@ast
Shen-Ying Zhang
@en
Shen-Ying Zhang
@es
Shen-Ying Zhang
@fr
Shen-Ying Zhang
@nl
Shen-Ying Zhang
@sl
prefLabel
Shen-Ying Zhang
@ast
Shen-Ying Zhang
@en
Shen-Ying Zhang
@es
Shen-Ying Zhang
@fr
Shen-Ying Zhang
@nl
Shen-Ying Zhang
@sl
P1053
I-2685-2017
P106
P21
P31
P3829
P496
0000-0002-9449-3672