WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
about
Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesRab1 recruits WHAMM during membrane remodeling but limits actin nucleation.Arf1 and Arf6 promote ventral actin structures formed by acute activation of protein kinase C and SrcThe WAVE Regulatory Complex Links Diverse Receptors to the Actin CytoskeletonRetrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowthAllosteric N-WASP activation by an inter-SH3 domain linker in NckWAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.The Drosophila Arf1 homologue Arf79F is essential for lamellipodium formation.Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein.Homer3 regulates the establishment of neutrophil polarityWASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motilityUsing optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion.Myoblast fusion: lessons from flies and mice.Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filaments.Brefeldin A-inhibited ADP-ribosylation factor activator BIG2 regulates cell migration via integrin β1 cycling and actin remodeling.Cellular functions of WASP family proteins at a glance.ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology.Synergistic activation of p21-activated kinase 1 by phosphatidylinositol 4,5-bisphosphate and Rho GTPasesARP2/3-dependent growth in the plant kingdom: SCARs for life.Arf6 coordinates actin assembly through the WAVE complex, a mechanism usurped by Salmonella to invade host cells.CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.In vitro studies of actin filament and network dynamics.Structural features and interfacial properties of WH2, β-thymosin domains and other intrinsically disordered domains in the regulation of actin cytoskeleton dynamics.Self-organization of protrusions and polarity during eukaryotic chemotaxis.Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.Phagocytosis: receptors, signal integration, and the cytoskeleton.Biochemical reconstitution of the WAVE regulatory complex.Arf GTPase interplay with Rho GTPases in regulation of the actin cytoskeleton.Swiss Army Pathogen: The Salmonella Entry Toolkit.MYO6 is targeted by Salmonella virulence effectors to trigger PI3-kinase signaling and pathogen invasion into host cells.Inhibition of WAVE Regulatory Complex Activation by a Bacterial Virulence Effector Counteracts Pathogen PhagocytosisThe Arf GTPase-activating protein family is exploited by Salmonella enterica serovar Typhimurium to invade nonphagocytic host cells.Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sitesNanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion.ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis.A module for Rac temporal signal integration revealed with optogenetics.The WAVE Regulatory Complex and Branched F-Actin Counterbalance Contractile Force to Control Cell Shape and Packing in the Drosophila Eye.Molecular Control of Actin Dynamics In Vivo: Insights from Drosophila.
P2860
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P2860
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@ast
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@en
type
label
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@ast
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@en
prefLabel
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@ast
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@en
P2093
P2860
P356
P1476
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
@en
P2093
Daniel Humphreys
Emma J McGhie
Ole Hørning
Peter J Hume
P2860
P304
14449-14454
P356
10.1073/PNAS.1107666108
P407
P577
2011-08-15T00:00:00Z