The Ndc80 kinetochore complex directly modulates microtubule dynamics.
about
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingReview series: The functions and consequences of force at kinetochoresFrom equator to pole: splitting chromosomes in mitosis and meiosisRNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated ratsSka3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.Structural basis for microtubule recognition by the human kinetochore Ska complexAccurate phosphoregulation of kinetochore-microtubule affinity requires unconstrained molecular interactions.Kinetochores require oligomerization of Dam1 complex to maintain microtubule attachments against tension and promote biorientation.Multisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity.Catch and release: how do kinetochores hook the right microtubules during mitosis?The contribution of αβ-tubulin curvature to microtubule dynamics.Force is a signal that cells cannot ignore.Phosphoregulation promotes release of kinetochores from dynamic microtubules via multiple mechanismsReconstitution of a prokaryotic minus end-tracking system using TubRC centromeric complexes and tubulin-like protein TubZ filaments.Minimal model for collective kinetochore-microtubule dynamics.Complications dawn for kinetochore regulation by AuroraHec1 Tail Phosphorylation Differentially Regulates Mammalian Kinetochore Coupling to Polymerizing and Depolymerizing Microtubules.Systems genetics implicates cytoskeletal genes in oocyte control of cloned embryo quality.The KMN protein network--chief conductors of the kinetochore orchestraThe internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.Coupling unbiased mutagenesis to high-throughput DNA sequencing uncovers functional domains in the Ndc80 kinetochore protein of Saccharomyces cerevisiae.Highly Transient Molecular Interactions Underlie the Stability of Kinetochore-Microtubule Attachment During Cell Division.Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation.Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments.Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Linked in: formation and regulation of microtubule attachments during chromosome segregation.Modelling chromosome dynamics in mitosis: a historical perspective on models of metaphase and anaphase in eukaryotic cells.A Molecular View of Kinetochore Assembly and Function.Understanding force-generating microtubule systems through in vitro reconstitution.Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism.A mathematical model of force generation by flexible kinetochore-microtubule attachments.Purification and characterisation of the fission yeast Ndc80 complexThe Ska complex promotes Aurora B activity to ensure chromosome biorientation.Preparation of segmented microtubules to study motions driven by the disassembling microtubule ends.A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset.A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments.Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex.Biophysics of Microtubule End Coupling at the Kinetochore.Aberrant Meiotic Modulation Partially Contributes to the Lower Germination Rate of Pollen Grains in Maize (Zea mays L.) Under Low Nitrogen Supply.
P2860
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P2860
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@ast
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@en
type
label
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@ast
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@en
prefLabel
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@ast
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@en
P2093
P2860
P356
P1476
The Ndc80 kinetochore complex directly modulates microtubule dynamics.
@en
P2093
Breanna S Vollmar
Charles L Asbury
Daniel R Gestaut
Neil T Umbreit
Tamir Gonen
P2860
P304
16113-16118
P356
10.1073/PNAS.1209615109
P407
P577
2012-08-20T00:00:00Z