Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing.
about
Ubiquitylation-dependent localization of PLK1 in mitosisThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingThe final link: tapping the power of chemical genetics to connect the molecular and biologic functions of mitotic protein kinasesRegulation of kinetochore-microtubule attachments through homeostatic control during mitosisMolecular dynamics of PLK1 during mitosisUsp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis.Multiple requirements of PLK1 during mouse oocyte maturationThe Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic ComplementationDynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunitDecoding Polo-like kinase 1 signaling along the kinetochore-centromere axisKinetic framework of spindle assembly checkpoint signallingSpatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanismsThe kinetochoreSpatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes.DNA-damage response during mitosis induces whole-chromosome missegregationThe condensin component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores.Distinct organization and regulation of the outer kinetochore KMN network downstream of CENP-C and CENP-TThe Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.CYLD-mediated signaling and diseases.Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1.Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization.DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age.Spindle Assembly and Chromosome Segregation Requires Central Spindle Proteins in Drosophila Oocytes.Mitotic kinase cascades orchestrating timely disjunction and movement of centrosomes maintain chromosomal stability and prevent cancer.Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpointGain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignanciesMaking an effective switch at the kinetochore by phosphorylation and dephosphorylation.Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis.Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis.Deciphering the spatio-temporal regulation of entry and progression through mitosis.Linked in: formation and regulation of microtubule attachments during chromosome segregation.Stressing mitosis to death.Polo-like kinases: structural variations lead to multiple functions.The Elephant in the Room: The Role of Microtubules in Cancer.Chromosome misalignments induce spindle-positioning defects.Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregationLiving in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.The equilibrium of ubiquitination and deubiquitination at PLK1 regulates sister chromatid separation.
P2860
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P2860
Polo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@ast
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@en
type
label
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@ast
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@en
prefLabel
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@ast
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@en
P2093
P2860
P356
P1476
Polo-like kinase-1 regulates k ...... spindle checkpoint silencing.
@en
P2093
Michael A Lampson
Olga Davydenko
P2860
P304
P356
10.1083/JCB.201205090
P407
P577
2012-08-01T00:00:00Z