Lithium rescues synaptic plasticity and memory in Down syndrome mice. - Wikidata - awgldk - TriplyDB

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

http://www.wikidata.org/entity/Q30530902

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A new look at an old drug: neuroprotective effects and therapeutic potentials of lithium salts Timing of therapies for Down syndrome: the sooner, the better Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations.Integrin-linked Kinase is Essential for Environmental Enrichment Enhanced Hippocampal Neurogenesis and Memory.Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives.Lithium ameliorates autistic-like behaviors induced by neonatal isolation in rats.Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts.Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome Therapeutic benefits of delayed lithium administration in the neonatal rat after cerebral hypoxia-ischemia.Type 3 diabetes is sporadic Alzheimer׳s disease: mini-review.Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3.Chronic P7C3 treatment restores hippocampal neurogenesis in the Ts65Dn mouse model of Down Syndrome [Corrected].Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome.Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity.Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory.Lithium increases proliferation of hippocampal neural stem/progenitor cells and rescues irradiation-induced cell cycle arrest in vitro.Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders.MDM2 inhibition rescues neurogenic and cognitive deficits in a mouse model of fragile X syndrome Lithium treatment alleviates impaired cognition in a mouse model of fragile X syndrome.Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits Neurosteroids Involvement in the Epigenetic Control of Memory Formation and Storage.Tau passive immunization inhibits not only tau but also Aβ pathology Lithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV.The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments.New innovations: therapeutic opportunities for intellectual disabilities.Wnts in adult brain: from synaptic plasticity to cognitive deficiencies.Hippocampal Wnt Signaling: Memory Regulation and Hormone Interactions.GSK-3β deletion in dentate gyrus excitatory neuron impairs synaptic plasticity and memory.Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome).The brain, sirtuins, and ageing.Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat brain.Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability.Isoflurane Is More Deleterious to Developing Brain Than Desflurane: The Role of the Akt/GSK3β Signaling Pathway.Rodent models in Down syndrome research: impact and future opportunities.Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila.Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice.

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Lithium rescues synaptic plasticity and memory in Down syndrome mice.

http://www.wikidata.org/entity/Q30530902

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

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Lithium rescues synaptic plasticity and memory in Down syndrome mice.

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type

label

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

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Lithium rescues synaptic plasticity and memory in Down syndrome mice.

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prefLabel

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

@ast

Lithium rescues synaptic plasticity and memory in Down syndrome mice.

@en

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Journal of Clinical Investigation

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Lithium rescues synaptic plasticity and memory in Down syndrome mice.

@en

P2093

Andrea Contestabile

http://www.w3.org/2001/XMLSchema#string

Barbara Greco

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Diego Ghezzi

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Fabio Benfenati

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Laura Gasparini

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Valter Tucci

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P2860

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

Synaptic integration and plasticity of new neurons in the adult hippocampus

The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome

In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

Endometrial cell counts in recurrent miscarriage: a comparison of counting methods

Lentiviral vectors to probe and manipulate the Wnt signaling pathway

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

A functional role for adult hippocampal neurogenesis in spatial pattern separation

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348-361

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10.1172/JCI64650

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1

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123

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2012-12-03T00:00:00Z

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3533293

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