Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease - Wikidata - awgldk - TriplyDB

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

http://www.wikidata.org/entity/Q30537842

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Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's Disease Oxidative stress and Parkinson's disease Mouse models of Parkinson's disease associated with mitochondrial dysfunction The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Ten years of Nature Reviews Neuroscience: insights from the highly cited Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease Principal Component Analysis of Multimodal Neuromelanin MRI and Dopamine Transporter PET Data Provides a Specific Metric for the Nigral Dopaminergic Neuronal Density Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.The role of iron in brain ageing and neurodegenerative disorders.Phagocytosis of microglia in the central nervous system diseases MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration Potential biomarkers relating pathological proteins, neuroinflammatory factors and free radicals in PD patients with cognitive impairment: a cross-sectional study Neuromelanin is an immune stimulator for dendritic cells in vitro.Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity.Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions Neuromelanin inhibits CXCL10 expression in human astroglial cells.Proteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome.Investigation on Abnormal Iron Metabolism and Related Inflammation in Parkinson Disease Patients with Probable RBD.Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease.Effect and Potential Mechanism of Electroacupuncture Add-On Treatment in Patients with Parkinson's Disease.Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissection.Neuromelanin in parkinsonian disorders: an update.Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.Direct intranigral injection of dopaminochrome causes degeneration of dopamine neurons Human neuromelanin: an endogenous microglial activator for dopaminergic neuron death The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function β-Propeller protein-associated neurodegeneration: a new X-linked dominant disorder with brain iron accumulation.Role and mechanism of microglial activation in iron-induced selective and progressive dopaminergic neurodegeneration.Inflaming the diseased brain: a role for tainted melanins.Systematic analysis of microarray datasets to identify Parkinson's disease‑associated pathways and genes.The neuroprotective effects of apocynin.Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors.Autoimmunity, dendritic cells and relevance for Parkinson's disease.Neuronal vulnerability, pathogenesis, and Parkinson's disease Iron accumulation in Parkinson's disease.Neuronal vulnerability, pathogenesis, and Parkinson's disease.Melanin affinity and its possible role in neurodegeneration.Innate immunity and neuroinflammation.Does restraining nitric oxide biosynthesis rescue from toxins-induced parkinsonism and sporadic Parkinson's disease?

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Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

http://www.wikidata.org/entity/Q30537842

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

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name

Neuromelanin activates microgl ...... ression of Parkinson's disease

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Neuromelanin activates microgl ...... ression of Parkinson's disease

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Neuromelanin activates microgl ...... ression of Parkinson's disease

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Neuromelanin activates microgl ...... ression of Parkinson's disease

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Neuromelanin activates microgl ...... ression of Parkinson's disease

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Neurotoxicity Research

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Neuromelanin activates microgl ...... ression of Parkinson's disease

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Albert R Wielgus

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Alberto Albertini

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Belinda Wilson

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Colin F Chignell

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Danielle Joset

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Fabio A Zucca

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Jau-Shyong Hong

http://www.w3.org/2001/XMLSchema#string

Jie Liu

http://www.w3.org/2001/XMLSchema#string

John Loike

http://www.w3.org/2001/XMLSchema#string

Kester Phillips

http://www.w3.org/2001/XMLSchema#string

P2860

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease

Parkinson's disease: mechanisms and models

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

Presynaptic recording of quanta from midbrain dopamine neurons and modulation of the quantal size.

Description of Parkinson's disease as a clinical syndrome.

Disease model: Parkinson's disease.

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics.

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1

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19

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Serge Przedborski

Vernice Jackson-Lewis

David S. Miller

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2009-12-03T00:00:00Z

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40444296

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1035329232

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19957214

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Parkinson's disease

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3603276

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