Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment
about
pH sensing via bicarbonate-regulated "soluble" adenylyl cyclase (sAC)Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMPCrystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonateStructural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulinMolecular details of cAMP generation in mammalian cells: a tale of two systemsRole of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulationThe role of soluble adenylyl cyclase in neurite outgrowthCrystal structure of the guanylyl cyclase Cya2Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosaCrystal structure of Cmr2 suggests a nucleotide cyclase-related enzyme in type III CRISPR-Cas systemsCrystal Structure of Human Soluble Adenylate Cyclase Reveals a Distinct, Highly Flexible Allosteric Bicarbonate Binding PocketIntracellular cAMP signaling by soluble adenylyl cyclase.Structural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes-implications for cyclase catalysis and evolutionSubstrate specificity determinants of class III nucleotidyl cyclasesA bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coliA phosphodiesterase 2A isoform localized to mitochondria regulates respirationRegulation of nuclear PKA revealed by spatiotemporal manipulation of cyclic AMP.Structure-based development of novel adenylyl cyclase inhibitorsCO(2) acts as a signalling molecule in populations of the fungal pathogen Candida albicansModulation of NaCl absorption by [HCO(3)(-)] in the marine teleost intestine is mediated by soluble adenylyl cyclaseDecreased soluble adenylyl cyclase activity in cystic fibrosis is related to defective apical bicarbonate exchange and affects ciliary beat frequency regulation.New structural forms of a mycobacterial adenylyl cyclase Rv1625c.Physiological carbon dioxide, bicarbonate, and pH sensingIdentification of a haem domain in human soluble adenylate cyclase.Soluble adenylyl cyclase in health and disease.Central role of soluble adenylyl cyclase and cAMP in sperm physiology.Cyanobacterial two-component proteins: structure, diversity, distribution, and evolution.Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling.A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in soluble adenylyl cyclase knockout miceSoluble adenylyl cyclase activity is necessary for retinal ganglion cell survival and axon growth.Crystallization of the class IV adenylyl cyclase from Yersinia pestis.Mycobacterial adenylyl cyclases: biochemical diversity and structural plasticity.Biphasic role of calcium in mouse sperm capacitation signaling pathwaysFungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence.A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacteriumGuanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonateDifferent cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.Complex structure of type VI peptidoglycan muramidase effector and a cognate immunity protein.
P2860
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P2860
Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Bicarbonate activation of aden ...... closure and metal recruitment
@ast
Bicarbonate activation of aden ...... closure and metal recruitment
@en
type
label
Bicarbonate activation of aden ...... closure and metal recruitment
@ast
Bicarbonate activation of aden ...... closure and metal recruitment
@en
prefLabel
Bicarbonate activation of aden ...... closure and metal recruitment
@ast
Bicarbonate activation of aden ...... closure and metal recruitment
@en
P2093
P2860
P356
P1476
Bicarbonate activation of aden ...... closure and metal recruitment
@en
P2093
Clemens Steegborn
Tatiana N Litvin
P2860
P2888
P356
10.1038/NSMB880
P577
2004-12-26T00:00:00Z