Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons

Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons

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http://www.wikidata.org/entity/Q30542949
Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal NeuronsThe Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and DiseasesDendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neuronsPre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's diseaseTau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's diseaseAPOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease.Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin InhibitorsReplenishment of microRNA-188-5p restores the synaptic and cognitive deficits in 5XFAD Mouse Model of Alzheimer's DiseaseMicrotubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection.Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brainDysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome.An Overview on the Clinical Development of Tau-Based Therapeutics.Atlas stumbled: kinesin light chain-1 variant E triggers a vicious cycle of axonal transport disruption and amyloid-β generation in Alzheimer's disease.Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane.
P2860

Amyloid-β oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons

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http://www.wikidata.org/entity/Q30542949
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2013 nî lūn-bûn
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Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@ast
Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@en
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Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@ast
Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@en
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Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@ast
Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Amyloid-β oligomers induce tau ...... n cultured hippocampal neurons
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932