Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders.
about
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)BLM helicase facilitates telomere replication during leading strand synthesis of telomeresScreening helix-threading peptides for RNA binding using a thiazole orange displacement assayGenetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae."One Ring to Bind Them All"-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.Acri-2,7-Py, a bright red-emitting DNA probe identified through screening of a distyryl dye library.Noncovalent binding and fluorogenic response of cyanine dyes to DNA homoquadruplex and PNA-DNA heteroquadruplex structures.Synthesis, analysis and biological evaluation of novel indolquinonecryptolepine analogues as potential anti-tumour agents.Contrasting enantioselective DNA preference: chiral helical macrocyclic lanthanide complex binding to DNA.Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine.A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1αMix and measure fluorescence screening for selective quadruplex binders.Circular dichroism and conformational polymorphism of DNA.Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor ActivityFrontiers of mass spectrometry in nucleic acids analysis.Mass spectrometry of G-quadruplex DNA: formation, recognition, property, conversion, and conformation.Methods for investigating G-quadruplex DNA/ligand interactions.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Label-free detection of kanamycin based on a G-quadruplex DNA aptamer-based fluorescent intercalator displacement assayAn oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex.Molecular recognition of T:G mismatched base pairs in DNA as studied by electrospray ionization mass spectrometry.Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.DNA-Targeted Inhibition of MGMT.New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer.Selective Targeting of G-Quadruplex Structures by a Benzothiazole-Based Binding Motif.Syntheses of polypyridyl metal complexes and studies of their interaction with quadruplex DNA.G-quadruplex-induced instability during leading-strand replication.G4 DNA: at risk in the genomeCopper(II) complexes of substituted salicylaldehyde dibenzyl semicarbazones: synthesis, cytotoxicity and interaction with quadruplex DNA.Thioflavin T as a fluorescence light-up probe for G4 formation.Optimization of the Alkyl Linker of TO Base Surrogate in Triplex-Forming PNA for Enhanced Binding to Double-Stranded RNA.A platinum complex that binds non-covalently to DNA and induces cell death via a different mechanism than cisplatin.A tri-copper(II) complex displaying DNA-cleaving properties and antiproliferative activity against cancer cells.Biological and cytoselective anticancer properties of copper(II)-polypyridyl complexes modulated by auxiliary methylated glycine ligand.Studies on characterization, telomerase inhibitory properties and G-quadruplex binding of η6-arene ruthenium complexes with 1,10-phenanthroline-derived ligands.
P2860
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P2860
Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Ligands playing musical chairs ...... elective G-quadruplex binders.
@ast
Ligands playing musical chairs ...... elective G-quadruplex binders.
@en
type
label
Ligands playing musical chairs ...... elective G-quadruplex binders.
@ast
Ligands playing musical chairs ...... elective G-quadruplex binders.
@en
prefLabel
Ligands playing musical chairs ...... elective G-quadruplex binders.
@ast
Ligands playing musical chairs ...... elective G-quadruplex binders.
@en
P2093
P1433
P1476
Ligands playing musical chairs ...... elective G-quadruplex binders.
@en
P2093
D Monchaud
H Bertrand
J-L Mergny
M-P Teulade-Fichou
N Smargiasso
V Gabelica
P304
P356
10.1016/J.BIOCHI.2008.02.019
P577
2008-03-04T00:00:00Z