Inhibition of the TRPC5 ion channel protects the kidney filter - Wikidata - awgldk - TriplyDB

Inhibition of the TRPC5 ion channel protects the kidney filter

Inhibition of the TRPC5 ion channel protects the kidney filter

http://www.wikidata.org/entity/Q30559274

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Podocytes Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies Novel in vivo techniques to visualize kidney anatomy and function.Transient receptor potential canonical 4 and 5 proteins as targets in cancer therapeutics TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases Renal autoregulation in health and disease Intravital imaging of podocyte calcium in glomerular injury and disease.Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli.The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling.Structural analysis of how podocytes detach from the glomerular basement membrane under hypertrophic stress Review series: The cell biology of renal filtration.Canonical transient receptor potential 4 and its small molecule modulators.Gq signaling causes glomerular injury by activating TRPC6.Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels Effects of stromal interaction molecule 1 or Orai1 overexpression on the associated proteins and permeability of podocytes.Sirtuin1 Maintains Actin Cytoskeleton by Deacetylation of Cortactin in Injured Podocytes.Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.Role of renal TRP channels in physiology and pathology Drug discovery in focal and segmental glomerulosclerosis Calcium-permeable ion channels in the kidney.Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation.How many Achilles' heels does a podocyte have? An update on podocyte biology.The importance of podocyte adhesion for a healthy glomerulus.Nox and renal disease.Human genetics of nephrotic syndrome and the quest for precision medicine.Podocytes and the quest for precision medicines for kidney diseases.Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors.Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.Targeting the podocyte cytoskeleton: from pathogenesis to therapy in proteinuric kidney disease.Podocyte-actin dynamics in health and disease.Blocking peptides and molecular mimicry as treatment for kidney disease.Natural and synthetic flavonoid modulation of TRPC5 channels.Pharmacological inhibition of FSGS-related TRPC6 gain of function mutants by semisynthetic larixol-derived compounds.Cell-free measurements of brightness of fluorescently labeled antibodies.Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.Melanocortin 1 receptor agonist protects podocytes through catalase and RhoA activation.A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.The Hippo pathway regulator KIBRA promotes podocyte injury by inhibiting YAP signaling and disrupting actin cytoskeletal dynamics.

P2860

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P2860

Inhibition of the TRPC5 ion channel protects the kidney filter

http://www.wikidata.org/entity/Q30559274

description

2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Inhibition of the TRPC5 ion channel protects the kidney filter

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Inhibition of the TRPC5 ion channel protects the kidney filter

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Inhibition of the TRPC5 ion channel protects the kidney filter

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Inhibition of the TRPC5 ion channel protects the kidney filter

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Inhibition of the TRPC5 ion channel protects the kidney filter

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Inhibition of the TRPC5 ion channel protects the kidney filter

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Journal of Clinical Investigation

P1476

Inhibition of the TRPC5 ion channel protects the kidney filter

@en

P2093

Anna Greka

http://www.w3.org/2001/XMLSchema#string

Antonio Riccio

http://www.w3.org/2001/XMLSchema#string

Astrid Weins

http://www.w3.org/2001/XMLSchema#string

Constantine Tarabanis

http://www.w3.org/2001/XMLSchema#string

Corey R Hopkins

http://www.w3.org/2001/XMLSchema#string

Dequan Tian

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Hanna Wallentin

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Hans Heid

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Lisa Buvall

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Philip Castonguay

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P2860

Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

TRPC channel activation by extracellular thioredoxin

Essential role for TRPC5 in amygdala function and fear-related behavior.

Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes

Cell biology and pathology of podocytes

Sodium leak channels in neuronal excitability and rhythmic behaviors

Calcium regulates podocyte actin dynamics.

TRPC5 is a regulator of hippocampal neurite length and growth cone morphology

Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling

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5298-5309

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scholarly article

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10.1172/JCI71165

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12

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123

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Craig W. Lindsley

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2013-11-15T00:00:00Z

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24231357

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3859394

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