SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.
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Two-pore Domain Potassium Channels in AstrocytesIndividual IKs channels at the surface of mammalian cells contain two KCNE1 accessory subunits.Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels.TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.Formation of Functional Heterodimers by TREK-1 and TREK-2 Two-pore Domain Potassium Channel Subunits.SUMOylation of NaV1.2 channels mediates the early response to acute hypoxia in central neurons.Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia.Potassium channels: structures, diseases, and modulators.The role of K₂p channels in anaesthesia and sleep.The family of K2P channels: salient structural and functional properties.Mitochondrial mechanisms of neuronal rescue by F-68, a hydrophilic Pluronic block co-polymer, following acute substrate deprivation.Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.Kv7 channels in the nucleus accumbens are altered by chronic drinking and are targets for reducing alcohol consumption.SUMOylation determines the voltage required to activate cardiac IKs channels.Eschewing ischemia or responding to it.Understanding the Cap Structure in K2P Channels.Heterodimerization of two pore domain K+ channel TASK1 and TALK2 in living heterologous expression systems.Oxygen and mitochondrial inhibitors modulate both monomeric and heteromeric TASK-1 and TASK-3 channels in mouse carotid body type-1 cells.Emerging Roles of TWIK-1 Heterodimerization in the Brain.TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines.The Insensitivity of TASK-3 K₂P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap StructureTWIK-1/TASK-3 heterodimeric channels contribute to the neurotensin-mediated excitation of hippocampal dentate gyrus granule cells
P2860
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P2860
SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@ast
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@en
type
label
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@ast
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@en
prefLabel
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@ast
SUMOylation silences heterodim ...... in cerebellar granule neurons.
@en
P2093
P2860
P1433
P1476
SUMOylation silences heterodim ...... in cerebellar granule neurons
@en
P2093
Jeremy D Marks
Leandro Zuniga
Leigh D Plant
P2860
P356
10.1126/SCISIGNAL.2003431
P577
2012-11-20T00:00:00Z