Vascular COX-2 modulates blood pressure and thrombosis in mice. - Wikidata - awgldk - TriplyDB

Vascular COX-2 modulates blood pressure and thrombosis in mice.

Vascular COX-2 modulates blood pressure and thrombosis in mice.

http://www.wikidata.org/entity/Q30562262

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Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering Inhibition of cyclooxygenase-2 in hematopoietic cells results in salt-sensitive hypertension Prediction of the potency of mammalian cyclooxygenase inhibitors with ensemble proteochemometric modeling.An Update of Microsomal Prostaglandin E Synthase-1 and PGE2 Receptors in Cardiovascular Health and Diseases Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation Use of genetic data to guide therapy in arterial disease.Hepatic ischemia and reperfusion injury in the absence of myeloid cell-derived COX-2 in mice.Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.In situ click chemistry generation of cyclooxygenase-2 inhibitors.Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice.Physiology. COX-2 inhibitors and cardiovascular risk.Cyclooxygenase-2-derived prostaglandin E₂ promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor.Advances in NSAID development: evolution of diclofenac products using pharmaceutical technology LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression Cyclooxygenases 1 and 2 differentially regulate blood pressure and cerebrovascular responses to acute and chronic intermittent hypoxia: implications for sleep apnea.A cyclooxygenase-2-dependent prostaglandin E2 biosynthetic system in the Golgi apparatus Association of cyclooxygenase-2 genetic variant with cardiovascular disease.Vasomotor Reaction to Cyclooxygenase-1-Mediated Prostacyclin Synthesis in Carotid Arteries from Two-Kidney-One-Clip Hypertensive Mice.Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice.Matrix-based Molecular Descriptors for Prospective Virtual Compound Screening.Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system.The Chemistry and Biology of Nakiterpiosin - C-nor-D-Homosteroids.Cell selective cardiovascular biology of microsomal prostaglandin E synthase-1.Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model.Cardiovascular Consequences of Prostanoid I Receptor Deletion in Microsomal Prostaglandin E Synthase-1-Deficient Hyperlipidemic Mice.Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.Constitutive activation of AMPK α1 in vascular endothelium promotes high-fat diet-induced fatty liver injury: role of COX-2 induction.Role of E-type prostaglandin receptor EP3 in the vasoconstrictor activity evoked by prostacyclin in thromboxane-prostanoid receptor deficient mice.Cyclooxygenase-2 in endothelial and vascular smooth muscle cells restrains atherogenesis in hyperlipidemic mice.New roles for old pathways? A circuitous relationship between reactive oxygen species and cyclo-oxygenase in hypertension.Clocks and cardiovascular function.Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways.Cardiovascular disease and non-steroidal anti-inflammatory drug prescribing in the midst of evolving guidelines.Identification and Characterization of Novel Microsomal Prostaglandin E Synthase-1 Inhibitors for Analgesia.Design, Synthesis, and Evaluation of an (18)F-Labeled Radiotracer Based on Celecoxib-NBD for Positron Emission Tomography (PET) Imaging of Cyclooxygenase-2 (COX-2).Cardiovascular effects of cyclooxygenase-2 inhibitors: a mechanistic and clinical perspective.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

http://www.wikidata.org/entity/Q30562262

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2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012 թվականի մայիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Vascular COX-2 modulates blood pressure and thrombosis in mice.

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Science Translational Medicine

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Vascular COX-2 modulates blood pressure and thrombosis in mice

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Colin D Funk

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Ellen Puré

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Emanuela Ricciotti

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Garret A FitzGerald

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Gavin Landesberg

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Irene Crichton

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Soon Yew Tang

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Weichen Wu

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Ying Yu

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Zhou Yu

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Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies

Human cyclooxygenase-2 cDNA

Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials

Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function

Role of prostacyclin in the cardiovascular response to thromboxane A2

Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Restricted inactivation of serum response factor to the cardiovascular system

Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

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Gregory R Grant

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