Rapid disorganization of mechanically interacting systems of mammary acini.
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Internal strain drives spontaneous periodic buckling in collagen and regulates remodeling.Interplay of active processes modulates tension and drives phase transition in self-renewing, motor-driven cytoskeletal networks.Tensile Forces Originating from Cancer Spheroids Facilitate Tumor InvasionEngineering cancer microenvironments for in vitro 3-D tumor models.Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices.Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration.Collagen Gels with Different Fibrillar Microarchitectures Elicit Different Cellular ResponsesMatrix Mechanosensing: From Scaling Concepts in 'Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer.Long-range force transmission in fibrous matrices enabled by tension-driven alignment of fibersPiezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line.Dynamic reciprocity between cells and their microenvironment in reproduction.Breast Cancer Cell Line Aggregate Morphology Does Not Predict Invasive CapacityRho GEFs and GAPs: emerging integrators of extracellular matrix signalingCell-mediated fibre recruitment drives extracellular matrix mechanosensing inĀ engineered fibrillar microenvironments.Multiscale mechanobiology: computational models for integrating molecules to multicellular systems.Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments.Collective cancer cell invasion induced by coordinated contractile stresses.Fibrous nonlinear elasticity enables positive mechanical feedback between cells and ECMs.Highly aligned stromal collagen is a negative prognostic factor following pancreatic ductal adenocarcinoma resection.The portal fibroblast: not just a poor man's stellate cell.Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes.Multicellular tumor invasion and plasticity in biomimetic materials.Role of suspended fiber structural stiffness and curvature on single-cell migration, nucleus shape, and focal-adhesion-cluster length.Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease.Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.Human pancreatic stellate cells modulate 3D collagen alignment to promote the migration of pancreatic ductal adenocarcinoma cells.Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation.Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion.Stress-induced plasticity of dynamic collagen networks.Local extracellular matrix alignment directs cellular protrusion dynamics and migration through Rac1 and FAK.Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics.Physical models of collective cell motility: from cell to tissue.Mechanical Characterization of Microengineered Epithelial Cysts by Using Atomic Force Microscopy.Alignment and nonlinear elasticity in biopolymer gels.Periductal stromal collagen topology of pancreatic ductal adenocarcinoma differs from that of normal and chronic pancreatitis.Tendon healing affects the multiscale mechanical, structural and compositional response of tendon to quasi-static tensile loading.Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces.Nonlinear Elasticity of the ECM Fibers Facilitates Efficient Intercellular Communication
P2860
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P2860
Rapid disorganization of mechanically interacting systems of mammary acini.
description
2013 nĆ® lÅ«n-bĆ»n
@nan
2013 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Ō“Õ„ÕÆÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
Õ¤ÕøÖÕ”Õ®
@hyw
2013 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ¤Õ„ÕÆÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2013幓ć®č«ę
@ja
2013幓č«ę
@yue
2013幓č«ę
@zh-hant
2013幓č«ę
@zh-hk
2013幓č«ę
@zh-mo
2013幓č«ę
@zh-tw
2013幓č®ŗę
@wuu
name
Rapid disorganization of mechanically interacting systems of mammary acini.
@ast
Rapid disorganization of mechanically interacting systems of mammary acini.
@en
type
label
Rapid disorganization of mechanically interacting systems of mammary acini.
@ast
Rapid disorganization of mechanically interacting systems of mammary acini.
@en
prefLabel
Rapid disorganization of mechanically interacting systems of mammary acini.
@ast
Rapid disorganization of mechanically interacting systems of mammary acini.
@en
P2093
P2860
P50
P356
P1476
Rapid disorganization of mechanically interacting systems of mammary acini.
@en
P2093
James A Sethian
Jan T Liphardt
Luke Cassereau
Quanming Shi
P2860
P304
P356
10.1073/PNAS.1311312110
P407
P577
2013-12-30T00:00:00Z