A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model.
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Serotonin synthesis, release and reuptake in terminals: a mathematical modelPositron Emission Tomography Imaging of Tumor Cell Metabolism and Application to Therapy Response MonitoringLabelled alpha-methyl-L-tryptophan as a tracer for the study of the brain serotonergic systemAlpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism.5-HT radioligands for human brain imaging with PET and SPECTIncreased tryptophan uptake on PET has strong independent prognostic value in patients with a previously treated high-grade glioma.Differential kinetics of α-[¹¹C]methyl-L-tryptophan on PET in low-grade brain tumors.Comparison of amino acid positron emission tomographic radiotracers for molecular imaging of primary and metastatic brain tumors.Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan.Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.Tryptophan PET-defined gross tumor volume offers better coverage of initial progression than standard MRI-based planning in glioblastoma patientsDevelopment of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Measuring serotonin synthesis: from conventional methods to PET tracers and their (pre)clinical implications.Clinical significance of tryptophan metabolism in the nontumoral hemisphere in patients with malignant gliomaThe lumped constant of α-methyl-l-tryptophan is not influenced by drugs acting through serotonergic system.Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas.Quantitative PET imaging of tryptophan accumulation in gliomas and remote cortex: correlation with tumor proliferative activityImaging cerebral tryptophan metabolism in brain tumor-associated depression.Imaging of serotonin mechanisms in epilepsyTryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlatesDifferences between males and females in rates of serotonin synthesis in human brain.Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder.Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of GlioblastomaAccurate differentiation of recurrent gliomas from radiation injury by kinetic analysis of α-11C-methyl-L-tryptophan PET.Differentiation of glioblastomas from metastatic brain tumors by tryptophan uptake and kinetic analysis: a positron emission tomographic study with magnetic resonance imaging comparison.Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors.AGN-2979, an inhibitor of tryptophan hydroxylase activation, does not affect serotonin synthesis in Flinders Sensitive Line rats, a rat model of depression, but produces a significant effect in Flinders Resistant Line rats.α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions.Densities of serotonergic projections as revealed by in situ synthesised labelled α-methyl-serotonin: an autoradiographic evaluation.Acute treatment with fluvoxamine elevates rat brain serotonin synthesis in some terminal regions: an autoradiographic study.5-HT2A receptor antagonist M100907 reduces serotonin synthesis: an autoradiographic studyHuman brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L-tryptophan.Alpha-methyl-L-tryptophan as a tracer to study brain serotonergic system.Both acute and chronic buspirone treatments have different effects on regional 5-HT synthesis in Flinders Sensitive Line rats (a rat model of depression) than in control rats.[(11)C]5-HTP and microPET are not suitable for pharmacodynamic studies in the rodent brain.Acute effects of combining citalopram and pindolol on regional brain serotonin synthesis in sham operated and olfactory bulbectomized ratsIn vivo-synthesized radioactively labelled alpha-methyl serotonin as a selective tracer for visualization of brain serotonin neurons.Alpha-[11C]methyl-L-tryptophan uptake in patients with periventricular nodular heterotopia and epilepsy.Alpha-methyltryptophan metabolism in rat pineal gland and brain.Rapid feasibility studies of tracers for positron emission tomography: high-resolution PET in small animals with kinetic analysis.
P2860
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P2860
A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
A new method to measure brain ...... c data for a biological model.
@ast
A new method to measure brain ...... c data for a biological model.
@en
type
label
A new method to measure brain ...... c data for a biological model.
@ast
A new method to measure brain ...... c data for a biological model.
@en
prefLabel
A new method to measure brain ...... c data for a biological model.
@ast
A new method to measure brain ...... c data for a biological model.
@en
P2093
P356
P1476
A new method to measure brain ...... c data for a biological model.
@en
P2093
S Nagahiro
T L Sourkes
Y L Yamamoto
P356
10.1038/JCBFM.1990.1
P577
1990-01-01T00:00:00Z