Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
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Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral statesUnmet needs of patients with narcolepsy: perspectives on emerging treatment optionsREM Sleep at its Core - Circuits, Neurotransmitters, and PathophysiologyNeurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleepCataplexy and Its Mimics: Clinical Recognition and Management.The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process.Chemogenetic stimulation of the hypoglossal neurons improves upper airway patencyTo ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin-knockout mice.Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli.Hypocretin/Orexin Peptides Alter Spike Encoding by Serotonergic Dorsal Raphe Neurons through Two Distinct Mechanisms That Increase the Late AfterhyperpolarizationOptogenetic activation of serotonergic terminals facilitates GABAergic inhibitory input to orexin/hypocretin neurons.Inflammation-sleep interface in brain disease: TNF, insulin, orexinLentiviral vectors as tools to understand central nervous system biology in mammalian model organisms.Optogenetic Investigation of Arousal CircuitsChallenges in the development of therapeutics for narcolepsy.Hypocretins, Neural Systems, Physiology, and Psychiatric Disorders.GABAergic Neurons of the Central Amygdala Promote Cataplexy.Hypocretins and Arousal.Neural Circuitry of Wakefulness and Sleep.Rewiring brain circuits to block cataplexy in murine models of narcolepsy.Optogenetic activation of melanin-concentrating hormone neurons increases non-rapid eye movement and rapid eye movement sleep during the night in rats.Synchronous circadian voltage rhythms with asynchronous calcium rhythms in the suprachiasmatic nucleusNarcolepsy Type 1 as an Autoimmune Disorder: Evidence, and Implications for Pharmacological Treatment.Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity.Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.Orexin/Hypocretin System: Role in Food and Drug Overconsumption.Orexin/Hypocretin and Organizing Principles for a Diversity of Wake-Promoting Neurons in the Brain.Orexin research: patent news from 2016.New Neuroscience Tools That Are Identifying the Sleep-Wake Circuit.Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics.Cataplexy--clinical aspects, pathophysiology and management strategy.The anatomical, cellular and synaptic basis of motor atonia during rapid eye movement sleep.An alerting structure: human orexin receptor 1.Reduced Orexin System Function Contributes to Resilience to Repeated Social Stress.The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific Hypocretin/Orexin receptor 1-KO mice
P2860
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P2860
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@ast
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@en
type
label
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@ast
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@en
prefLabel
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@ast
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@en
P2093
P2860
P356
P1476
Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.
@en
P2093
Emi Hasegawa
Masashi Yanagisawa
Takeshi Sakurai
P2860
P304
P356
10.1172/JCI71017
P407
P577
2014-01-02T00:00:00Z