Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
about
A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptorsN-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in rats.Glutamate and its receptors in cancerGRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma.Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo.Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer.Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes.Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain.Identification of novel GRM1 mutations and single nucleotide polymorphisms in prostate cancer cell lines and tissues.Glutamate secretion and metabotropic glutamate receptor 1 expression during Kaposi's sarcoma-associated herpesvirus infection promotes cell proliferation.Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis.Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole.Glutamate signaling in benign and malignant disorders: current status, future perspectives, and therapeutic implications.Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.GRIK3: A novel oncogenic protein related to tumor TNM stage, lymph node metastasis, and poor prognosis of GC.The current management of brain metastasis in melanoma: a focus on riluzole.Metabotropic glutamate receptors in cancer.Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas.Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe (18) F-FITM.Octahydropyrrolo[3,4-c]pyrrole negative allosteric modulators of mGlu1.Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement in clinical cancer specimens.The miR-487b-3p/GRM3/TGFβ signaling axis is an important regulator of colon cancer tumorigenesisIntegrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities.Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo.Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo.[The cancer paradigm in pulmonary arterial hypertension: towards anti-remodeling therapies targeting metabolic dysfunction?]Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses.Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo
P2860
Q30406728-1D80869E-3B46-4B4E-81DD-7B85E5435167Q30435534-52358006-3033-4A2E-A973-71928C77B6ACQ34048497-E7F62C5B-7E64-46F0-8146-FBC3D544BE6BQ34411505-3863C408-F1BA-4FF1-919C-83593C607C8FQ34572217-04AD58B1-29C9-4C48-AF14-584029CED133Q34710990-AC3750A0-A8C9-4C57-9317-6340C4CA5F97Q34904277-906B2F97-80F2-4FBD-96ED-75CE91606A7FQ35070083-2301AAA0-4CBF-4D3E-AC83-AF191E5CE881Q35213199-392D4E3F-D426-4581-B554-81DF550ADFFCQ35315503-24E249C5-5E54-4343-AE14-B55293D581ABQ35752074-DE00652A-0F27-44DA-B2D3-E0F1592BC116Q36288488-902C92F4-EC77-4E05-AD7A-B4FD4126DA7BQ37121338-C17308F7-A134-4C82-9EB3-9A913C9CD7F0Q37540105-9A5F6A40-7E0C-4843-8450-F805C0A29CD0Q37626431-AE0679C6-A278-43AC-9DF0-F56C38233870Q38432265-ECF2B336-FBEC-4F20-B23E-0C0686862897Q38532696-FEC8B75B-5F3C-4A78-A3EB-8C08A6DB1F23Q38741884-44AB7408-790E-4070-9534-B451B97215C0Q38971337-A6128748-28D9-4A88-B8F5-92B23A18C1DFQ39014061-2B923D08-5709-4450-A05A-D05164C234E4Q41890142-E5F4560B-A031-4B5A-81C5-00BE6889D49CQ41906700-CAF179BD-BF9F-4461-9BBC-253EC057CE0EQ42081827-567C2FAD-3A63-4BA7-9603-4B7F4F2C9DA9Q46311036-1246C708-D66D-454C-93EF-8D708D9FE540Q49787772-16EF1E7A-397D-4EAD-96C7-0300203DC9E9Q50121078-8B78DAB5-2672-4025-BDCC-2B4CC3B0B1FFQ52312423-759DFA20-8334-46DE-8BDD-41F534B2D21AQ53063306-C5DA18E7-2D6D-487C-836B-A91B037A7802Q59137905-DCCA461B-2945-4AFE-BEBF-14DC2A201436
P2860
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@ast
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@en
type
label
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@ast
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@en
prefLabel
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@ast
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@en
P2093
P2860
P356
P1433
P1476
Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
@en
P2093
B J Wilimczyk
E Mastrantoni
J J Martino
K Degenhardt
S N La Cava
P2860
P2888
P304
P356
10.1038/ONC.2012.471
P407
P50
P577
2012-10-22T00:00:00Z
P5875
P6179
1022495006