Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.

Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.

Item
http://www.wikidata.org/entity/Q30576914
Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationUtility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound.Application of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect.Experimental models for predicting drug absorption and metabolism.Selecting oral bioavailability enhancing formulations during drug discovery and development.Physiologically based pharmacokinetic modeling in drug discovery and development: a pharmaceutical industry perspective.Mechanistic prediction of food effects for Compound A tablet using PBPK model.Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement.Food Effect in Humans: Predicting the Risk Through In Vitro Dissolution and In Vivo Pharmacokinetic Models.Use of preclinical dog studies and absorption modeling to facilitate late stage formulation bridging for a BCS II drug candidate.Application of Absorption Modeling in Rational Design of Drug Product Under Quality-by-Design Paradigm.Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status.Pharmacokinetics, pharmacodynamics and food effect of LB30870, a novel direct thrombin inhibitor, after single oral doses in healthy men.
P2860

Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.

Item
http://www.wikidata.org/entity/Q30576914
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Case studies for practical foo ...... and preclinical in vivo data.
@ast
Case studies for practical foo ...... and preclinical in vivo data.
@en
type
label
Case studies for practical foo ...... and preclinical in vivo data.
@ast
Case studies for practical foo ...... and preclinical in vivo data.
@en
prefLabel
Case studies for practical foo ...... and preclinical in vivo data.
@ast
Case studies for practical foo ...... and preclinical in vivo data.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P932
P356
P1433
P1476
Case studies for practical foo ...... and preclinical in vivo data.
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P932