Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study - Wikidata - awgldk - TriplyDB

Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study

Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study

http://www.wikidata.org/entity/Q30577157

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Magnetic resonance imaging striatal volumes: a biomarker for clinical trials in Huntington's disease Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin.Multivariate clustering of progression profiles reveals different depression patterns in prodromal Huntington disease.Statistical Approaches to Longitudinal Data Analysis in Neurodegenerative Diseases: Huntington's Disease as a Model.Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study Motor onset and diagnosis in Huntington disease using the diagnostic confidence level.Longitudinal Psychiatric Symptoms in Prodromal Huntington's Disease: A Decade of Data.T1ρ imaging in premanifest Huntington disease reveals changes associated with disease progression.Data quality assurance and control in cognitive research: Lessons learned from the PREDICT-HD study.Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease Machine learning in a graph framework for subcortical segmentation.The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease Improved high sensitivity screen for Huntington disease using a one-step triplet-primed PCR and melting curve assay.Functional connectivity of primary motor cortex is dependent on genetic burden in prodromal Huntington disease.Onset of Huntington's disease: can it be purely cognitive?Is There an Association of Physical Activity with Brain Volume, Behavior, and Day-to-day Functioning? A Cross Sectional Design in Prodromal and Early Huntington Disease.Multivariate semiparametric spatial methods for imaging data.Quantitative Electroencephalographic Analysis Provides an Early-Stage Indicator of Disease Onset and Progression in the zQ175 Knock-In Mouse Model of Huntington's Disease.COPPADIS-2015 (COhort of Patients with PArkinson's DIsease in Spain, 2015), a global--clinical evaluations, serum biomarkers, genetic studies and neuroimaging--prospective, multicenter, non-interventional, long-term study on Parkinson's disease prog Multivariate prediction of motor diagnosis in Huntington's disease: 12 years of PREDICT-HD Linking white matter and deep gray matter alterations in premanifest Huntington disease Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease Modeling Variability in the Progression of Huntington's Disease A Novel Modeling Approach Applied to Structural Imaging Markers from TRACK-HD.Network topology and functional connectivity disturbances precede the onset of Huntington's disease.Patterns of Co-Occurring Gray Matter Concentration Loss across the Huntington Disease Prodrome.Reverse Translation in Parkinson Disease The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers.Mapping the order and pattern of brain structural MRI changes using change-point analysis in premanifest Huntington's disease.Factors Associated With End-of-Life Planning in Huntington Disease.Cognitive Control, Learning, and Clinical Motor Ratings Are Most Highly Associated with Basal Ganglia Brain Volumes in the Premanifest Huntington's Disease Phenotype.Penalized nonlinear mixed effects model to identify biomarkers that predict disease progression.Validation of a prognostic index for Huntington's disease.Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.Huntington disease: a single-gene degenerative disorder of the striatum.The development of a new computer adaptive test to evaluate chorea in Huntington disease: HDQLIFE Chorea.Support Vector Hazards Machine: A Counting Process Framework for Learning Risk Scores for Censored Outcomes.Phenotype Characterization of HD Intermediate Alleles in PREDICT-HD.New measures to capture end of life concerns in Huntington disease: Meaning and Purpose and Concern with Death and Dying from HDQLIFE (a patient-reported outcomes measurement system).Preliminary analysis using multi-atlas labeling algorithms for tracing longitudinal change.Longitudinal diffusion changes in prodromal and early HD: Evidence of white-matter tract deterioration.

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Clinical and Biomarker Changes in Premanifest Huntington Disease Show Trial Feasibility: A Decade of the PREDICT-HD Study

http://www.wikidata.org/entity/Q30577157

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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FNAGI.2014.00078

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Frontiers in Aging Neuroscience

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Clinical and Biomarker Changes ...... Decade of the PREDICT-HD Study

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Cheryl J Erwin

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Deborah L Harrington

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Edmond M Chiu

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Elizabeth A McCusker

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Elizabeth H Aylward

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H Jeremy Bockholt

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Holly J Westervelt

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Martha A Nance

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PREDICT-HD Investigators and Coordinators of the Huntington Study Group

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Peter K Panegyres

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P2860

Self-paced timing detects and tracks change in prodromal Huntington disease.

Longitudinal change in regional brain volumes in prodromal Huntington disease

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.

Huntington disease: natural history, biomarkers and prospects for therapeutics.

Huntington's disease: from molecular pathogenesis to clinical treatment.

Progression in prediagnostic Huntington disease.

Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data.

Seven-year clinical follow-up of premanifest carriers of Huntington's disease.

Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study.

The Trail Making Test in prodromal Huntington disease: contributions of disease progression to test performance.

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78

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10.3389/FNAGI.2014.00078

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6

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Janet K. Williams

Jane S. Paulsen

Christopher A Ross

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2014-04-22T00:00:00Z

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262055513

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24795630

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Huntington disease

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4000999

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