A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
about
Platelet function and ageingWhen stem cells grow old: phenotypes and mechanisms of stem cell agingWNT-5A: signaling and functions in health and diseaseHematopoietic stem cell niche maintenance during homeostasis and regenerationThe reverse control of irreversible biological processesUbiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.Cholesterol selectively activates canonical Wnt signalling over non-canonical Wnt signalling.Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling.The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancersWnt/catenin signaling in adult stem cell physiology and disease.Concise review: hematopoietic stem cell aging and the prospects for rejuvenationRor2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescenceThe altered fate of aging satellite cells is determined by signaling and epigenetic changes.Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation.A decline in Wnt3a signaling is necessary for mesenchymal stem cells to proceed to replicative senescenceSeptic Shock in Advanced Age: Transcriptome Analysis Reveals Altered Molecular Signatures in Neutrophil Granulocytes.Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-cateninWnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells.HSC Aging and Senescent Immune Remodeling.Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome.Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.The non-canonical Wnt pathway negatively regulates dendritic cell differentiation by inhibiting the expansion of Flt3(+) lymphocyte-primed multipotent precursors.Microenvironmental regulation of hematopoietic stem cells and its implications in leukemogenesis.Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway.Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activityIdentification of novel genes and networks governing hematopoietic stem cell developmentNiche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cellsNoncanonical WNT-5A signaling impairs endogenous lung repair in COPDOsteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.Bone cell senescence: mechanisms and perspectives.Regulation of hematopoiesis by activators and inhibitors of Wnt signaling from the niche.Regulation of hematopoietic stem cell aging by the small RhoGTPase Cdc42Early B lymphocyte development: Similarities and differences in human and mouse.Hematopoietic stem cells: concepts, definitions, and the new reality.Ex vivo expansion of hematopoietic stem cells.The Wnt signaling pathway in cancer.CAMK2γ antagonizes mTORC1 activation during hepatocarcinogenesis.The mitochondrial metabolic checkpoint and aging of hematopoietic stem cells.WNT5A: a motility-promoting factor in Hodgkin lymphoma.
P2860
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P2860
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@ast
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@en
type
label
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@ast
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@en
prefLabel
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@ast
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
@en
P2093
P2860
P50
P356
P1433
P1476
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing
@en
P2093
Bettina Uberle
Christina Eckl
Gina Marka
Hartmut Geiger
Immanuel Andrä
Kalpana J Nattamai
Karin Dörr
Karin Scharffetter-Kochanek
Matthias Schiemann
P2860
P2888
P304
P356
10.1038/NATURE12631
P407
P577
2013-10-20T00:00:00Z
P6179
1033032811