Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage.
about
Perturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human diseaseHuman keratinocytes have two interconvertible modes of proliferation.A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.Genetics of gonadal stem cell renewalInhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell populationTailor made protein synthesis for HSCs.Systematic discovery of genetic modulation by Jumonji histone demethylases in DrosophilaOverexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice.Translational control in germline stem cell development.Cellular differences in protein synthesis regulate tissue homeostasis.Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast.Downregulation of rRNA transcription triggers cell differentiation.Transgenerational inheritance of diet-induced genome rearrangements in DrosophilaEffects of Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) in Tetrahymena Thermophila: Targeting the Ribosome.Alcohols inhibit translation to regulate morphogenesis in C. albicansTex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and ReprogrammingThe Regulation of rRNA Gene Transcription during Directed Differentiation of Human Embryonic Stem Cells.Role of the small subunit processome in the maintenance of pluripotent stem cellsCoordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during developmentRibosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cellsComparative transcriptomic analysis of silkworm Bmovo-1 and wild type silkworm ovary.tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription.Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis.Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell DifferentiationStem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer.REST regulation of gene networks in adult neural stem cells.Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors.Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe.p53, a translational regulator: contribution to its tumour-suppressor activity.Emerging roles of nucleolar and ribosomal proteins in cancer, development, and aging.Noncoding RNAs in Growth and Death of Cancer Cells.Hypertranscription in Development, Stem Cells, and Regeneration.Role of Chromatin Modifications in Drosophila Germline Stem Cell Differentiation.Mammary epithelial morphogenesis and early breast cancer. Evidence of involvement of basal components of the RNA Polymerase I transcription machinery.The Conserved RNA Exonuclease Rexo5 Is Required for 3' End Maturation of 28S rRNA, 5S rRNA, and snoRNAs.Isolation and functional interrogation of adult human prostate epithelial stem cells at single cell resolution.Ribosome biogenesis is dynamically regulated during osteoblast differentiation.FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.Protecting and Diversifying the Germline.Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells.
P2860
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P248
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P2860
Changes in rRNA transcription influence proliferation and cell fate within a stem cell lineage.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Changes in rRNA transcription ...... te within a stem cell lineage.
@ast
Changes in rRNA transcription ...... te within a stem cell lineage.
@en
type
label
Changes in rRNA transcription ...... te within a stem cell lineage.
@ast
Changes in rRNA transcription ...... te within a stem cell lineage.
@en
prefLabel
Changes in rRNA transcription ...... te within a stem cell lineage.
@ast
Changes in rRNA transcription ...... te within a stem cell lineage.
@en
P2093
P2860
P356
P1433
P1476
Changes in rRNA transcription ...... te within a stem cell lineage.
@en
P2093
Michael Buszczak
Nevine A Shalaby
Qiao Zhang
P2860
P304
P356
10.1126/SCIENCE.1246384
P407
P577
2014-01-01T00:00:00Z