Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics.

Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics.

Item
http://www.wikidata.org/entity/Q30585001
β-hairpin-mediated formation of structurally distinct multimers of neurotoxic prion peptidesSheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solutionSolvent microenvironments and copper binding alters the conformation and toxicity of a prion fragmentThe efficacy of tetracyclines in peripheral and intracerebral prion infection.Computational approaches to shed light on molecular mechanisms in biological processesStructural diversity and initial oligomerization of PrP106-126 studied by replica-exchange and conventional molecular dynamics simulationsPossible role of region 152-156 in the structural duality of a peptide fragment from sheep prion protein.Influence of gold-bipyridyl derivants on aggregation and disaggregation of the prion neuropeptide PrP106-126.Conformational polymorphism of the amyloidogenic peptide homologous to residues 113-127 of the prion protein.Helix-coil transition of PrP106-126: molecular dynamic study.The role of hydrophobic interactions in amyloidogenesis: example of prion-related polypeptides.C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage.The effect of a membrane-mimicking environment on the interactions of Cu2+ with an amyloidogenic fragment of chicken prion protein.
P2860

Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics.

Item
http://www.wikidata.org/entity/Q30585001
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Determination of solution conf ...... restrained molecular dynamics.
@ast
Determination of solution conf ...... restrained molecular dynamics.
@en
type
label
Determination of solution conf ...... restrained molecular dynamics.
@ast
Determination of solution conf ...... restrained molecular dynamics.
@en
prefLabel
Determination of solution conf ...... restrained molecular dynamics.
@ast
Determination of solution conf ...... restrained molecular dynamics.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Determination of solution conf ...... restrained molecular dynamics
@en
P2093
P2860
P304
P31
P356
10.1046/J.1432-1327.1999.00985.X
P407
P433
P478
P50
P577
P5875
P698
P921